296例Ⅱ期胸段食管鳞癌术后患者的预后分析  

An Analysis of Prognosis in 296 Cases with Thoracic Esophageal Squamous Cell Carcinoma Stage Ⅱ Postoperation

作　　者：沈飚[1,2] 高俊[1,2] 樊天友[1,2] 王健[1,2] 

机构地区：[1]南通市肿瘤医院 [2]南通大学附属肿瘤医院,江苏南通226361

出　　处：《肿瘤学杂志》2010年第9期732-734,共3页Journal of Chinese Oncology

摘　　要：[目的]探讨影响Ⅱ期胸段食管鳞癌术后预后的因素。[方法]回顾性分析南通市肿瘤医院胸外科2002年1月至2005年1月收治的296例单纯手术切除食管鳞癌患者的临床资料。[结果]全组总的1、3、5年生存率分别为86.8%(257/296)、54.0%(160/296)、42.9%(127/296)。ⅡA期和ⅡB期患者的5年生存率分别为51.3%(99/193)和27.2%(28/103)(P<0.001)。患者的性别、淋巴结转移、手术切缘情况、肿瘤浸润深度及组织分化程度均为预后影响因素(P<0.05),而患者年龄、肿瘤部位及肿瘤长度与预后无关(P>0.05)。[结论]影响Ⅱ期胸段食管鳞癌患者术后生存的主要因素有性别、淋巴结转移及手术切缘情况、肿瘤浸润深度及组织分化程度。[Purpose] To investigate the prognosis of the thoracic esophageal squamous cell carcinoma stageⅡ postoperation. [Methods] The clinical data of 296 cases with thoracic esophageal squamous cell carcinoma stage Ⅱ from Jan. 2002 to Jan,2005 underwent surgery alone were analyzed retro-spectively. [Results] The overall 1-,3-,5-year survival was 86.8%,54.0%,42.9%,respectively. The 5-year survival rates in stage ⅡA and stage ⅡB were 51.3%（99/193） and 27.2%（28/103）（P〈0.001） ,respectively. Gender,lymph node metastasis,surgical margin status,depth of invasion and differentia-tion related to prognosis,but age,tumor site and tumor size did not related to prognosis. [Conclu-sions] Gender,lymph node metastasis,surgical margin status,depth of invasion and differentiation are prognostic factors in thoracic esophageal squamous cell carcinoma stage Ⅱ postoperation.

关 键 词：食管癌 Ⅱ期 外科手术 生存期 预后因素 

分 类 号：R735.1[医药卫生—肿瘤]