急性脑梗死患者血清同型半胱氨酸和超敏C反应蛋白检测的临床意义  

Clinical significance of changes of serum homocysteine and High-sensitivity C-reactive protein levels in patients with acute cerebral infarction

作　　者：李慧[1] 王蓓[1] 徐蓓[1] 

机构地区：[1]江苏省连云港市第一人民医院,222002

出　　处：《中国医疗前沿》2010年第20期23-23,37,共2页China Healthcare Innovation

摘　　要：目的探讨急性脑梗死患者血清同型半胱氨酸(Hcy)和超敏C反应蛋白(hs-CRP)水平的变化及临床意义。方法应用EliSA法和免疫比浊法对36例急性脑梗死患者进行血清Hcy和hs-CRP水平测定,并与35名正常健康人作比较。结果急性脑梗死患者血清Hcy和hs-CRP水平均非常显著地高于正常人组(P<0.01),且血清Hcy水平与hs-CRP水平呈正相关(r=0.5872,P<0.01)。结论急性脑梗死患者血清Hcy和hs-CRP水平的升高与脑梗死的严重程度呈正相关,可作为预测急性脑梗死发生发展的敏感指标。Objective To explore the clinical significance of changes of serum Hcy and hs-CRP levels in the patients with acute cerebral infarction（ACI）.Methods Hcy（with EliSA）,hs-CRP（with immunoturbidimetry） levels were measured in 36 patients with acute cerebral infarction as well as in 35 contrals.Results The levels of serum Hcy and hs-CRP in the patients with ACI were significantly higher than those in contrals（P0.01）.Serum Hcy levels were positively correlated to hs-CRP levels（r=0.5872,P0.01）.Conclusions The levels of Hcy,and hs-CRP are markedly increased in the patients with ACI,which are positively correlated to the severity of ACI and may be taken as the sensitive biochemical markers for predicting its development.

关 键 词：急性脑梗死 同型半胱氨酸 超敏C反应蛋白 

分 类 号：R743.33[医药卫生—神经病学与精神病学]