肝血管周上皮样细胞肿瘤临床病理观察  

Perivascular epithelioid cell tumor of liver:clinicopathologic observations

作　　者：刘静[1] 郭华雄[1] 张柳[1] 袁璐[1] 

机构地区：[1]荆州市中心医院病理科,湖北荆州434020

出　　处：《诊断病理学杂志》2010年第5期353-355,共3页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨血管周上皮样细胞肿瘤(PEComa)的临床病理特点及鉴别诊断。方法报道1例发生于肝的血管周上皮样细胞肿瘤并对其临床表现、组织学形态、免疫表型及生物学行为进行分析,并复习相关文献。结果血管周上皮样细胞肿瘤是起源于血管周细胞的间叶性肿瘤,组织学上由单一的上皮样细胞组成,不含厚壁血管及脂肪组织,该肿瘤黑色素标记物HMB45(+)。结论血管周上皮样细胞肿瘤是一种非常罕见的间叶组织来源的肿瘤,具有独特的形态学和免疫组化特征,生物学行为不确定。临床以手术切除为主,且建议术后长期随访。Objective To explore the clinical pathologic features and differential diagnosis of perivasular epithelioid cell tumor of the liver. Methods A case of PEComa was reported in the liver, and related literatures were reviewd. Results The PEComa arised from the mesenchymal tissue. Histologically, the tumor was composed of epithelioid cell, without vascular or lipomatous component, and characterized by positive HMP,45 on immunohistochemistry. Conclusion The PEComa is a rare tumor in the liver, which has the unique morphological and immunohistochemical characteristics. The biologic behavior of the PEComa is unknown. Clinically, surgical removal is suggested, with a long-term follow-up.

关 键 词：肝 血管周上皮样细胞肿瘤 临床病理 

分 类 号：R735.7[医药卫生—肿瘤]