氟代脱氧葡萄糖在PET／CT致痫灶定位显像中的应用  

Application of 18S F-FDG PET/CT in epileptogenic zone localization

作　　者：王永玲[1] 张工化[1] 王清理[1] 王芬[1] 

机构地区：[1]漯河市中心医院PET/CT科,河南省漯河462000

出　　处：《中国基层医药》2010年第21期2919-2920,3026,共3页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨正电子药物18F氟代脱氧葡萄糖（18F-FDG）在正电子发射计算机（断层PET／CT）脑显像致痫灶定位中的应用。方法对32例癫痫患者行18F-FDG脑三维PET／CT显像，将其定位结果与头皮脑电图（EEG）、颅脑CT或MRI结果进行比较。结果PET／CT阳性检出率为90．6％（29／32），其中低代谢灶27例，高代谢灶2例，正常3例；EEG阳性检出率为65．6％（21／32），常规脑部CT或MRI阳性检出率为31．0％（10／32）。结论18F-FDG在PETJCT脑显像中对癫痫的定位诊断有较高的灵敏性和准确性。Objective To discuss the application of 18 F-FDG PET/CT in epileptogenie zone localization. Methods Tirty-two patients with epilepsies were studied with interietal 18F-FDG PET/CT cerebral imaging, and all of them had scalp EEG, CT or MRI results for eomparision. Results The sensitivity of 18F-FDG PET/CT was 90. 6% ,27 patients（84.5% ） showed focal hypometabolism,2 patients（6. 3% ） showed focal hypermetabohsm and rest 3 patients （9. 4% ） had negative result. The sensitivity of EEG was 65.6% （21/32）, the sensitivity of CT and MRI was 31.0% （10/32）. Conclusion 18F-FDG PET/CT was a sensitive and accurate image modality in the localization of epileptle loci.

关 键 词：氟脱氧葡萄糖F18 正电子发射断层显像技术 

分 类 号：R742[医药卫生—神经病学与精神病学]