经济决策的神经化学与遗传基础  

Neurochemical and genetic basis of economic decision-making

作　　者：马庆国[1,2] 沈强[1,2] 李典典[1,2] 卞军[1,2] 

机构地区：[1]浙江大学管理学院,杭州310058 [2]浙江大学神经管理学实验室,杭州310027

出　　处：《科学通报》2010年第32期3089-3096,共8页Chinese Science Bulletin

基　　金：国家自然科学基金重大研究计划重点支持项目(90924304);国家社会科学基金(08BJL054);教育部哲学社会科学研究重大课题攻关项目(09-JZD0006);浙江省社会科学基金(09CGGL008YBB;06CGSH06YB)资助

摘　　要：神经成像技术的快速发展,使得经济决策研究进入了一个新阶段,即在行为决策科学、行为经济学的基础上,借鉴自然科学的研究手段与方法开展跨学科领域的探索,神经经济学在本世纪诞生并迅猛发展.随着该交叉学科研究的进一步深入,遗传学、基因组学等更多自然科学学科也开始与经济决策研究结合,使得研究者从个体的微观视角对经济决策的理论与观点进行更为深入地理解和阐释.最新的研究表明,大脑内的神经递质与人们的包括经济决策在内的决策紧密相关,而决定大脑神经递质的遗传基因又通过影响神经递质的水平与功能,间接地影响人们的决策行为.本文以神经递质多巴胺、5-羟色胺、催产素为例,着重介绍大脑内的3种神经递质及其对应的相关基因与人们经济决策中风险决策、社会决策的密切联系与内在机理.With rapid advances in neuroimaging techniques,research on economic decision-making has entered into a new phase.A new field named ＇neuroeconomics＇ has emerged,based on behavioral decision science and behavioral economics.Neuroeconomics has rapidly advanced in the last decade,utilizing natural science approach.As this interdisciplinary field has developed,researchers have incorporated aspects of genetics and genomics to further extend theoretical research in economic decision-making from the micro-perspective of individuals.Recently,a growing body of evidence has suggested a close relationship between decision-making （e.g.economic decisions） and neurotransmitter systems in the brain.Moreover,the genes involved in neurotransmitter function have been found to influence decision-making behavior indirectly by regulating the level and function of neurotransmitters.This review focuses on three of the most exhaustively examined neurotransmitters,dopamine,serotonin and oxytocin,to elucidate the complex relationship between these neurotransmitters,the corresponding genes and risk as well as social decision-making.

关 键 词：经济决策 神经化学 遗传 神经递质 

分 类 号：F272.3[经济管理—企业管理]