口腔复发性阿弗他溃疡患者血液流变学与微量元素分析  

Analysis of Hemorrheology and trace elements contents in patients with oral recurrent aphthae ulcer

作　　者：刘鑫[1] 程颖[2] 邓蔓菁[3] 韩志国[2] 杨光玉[1] 董天贞[3] 

机构地区：[1]重庆市第三人民医院口腔科,重庆400014 [2]重庆市血液中心,重庆400015 [3]第三军医大学第三附属医院野战外科研究所口腔科,重庆400042

出　　处：《重庆医科大学学报》2010年第10期1569-1571,共3页Journal of Chongqing Medical University

摘　　要：目的:探讨血液流变学因素和相关微量元素在口腔复发性阿弗他溃疡(Recurrent aphthae ulcer,RAU)发病中的作用。方法:从献血志愿者中筛选出83例RAU患者,检测其血液流变学指标和血清微量元素Mg、Fe、Zn、Se、Cu含量,并与正常健康志愿者对照分析。结果:RAU患者全血粘度、全血还原粘度、血浆粘度、红细胞压积均高于对照组(P<0.05);红细胞电泳时间延长、红细胞沉降率降低(P<0.05);血清Zn、Se含量明显低于对照组(P<0.05),而Mg、Fe、Cu含量与对照组差异无明显统计学意义(P>0.05)。结论:RAU患者Zn和Se元素含量相对降低,血液流变学情况改变;本研究为临床上通过补充Zn和Se,以及改善血液循环的方式治疗RAU提供了参考依据。Objective：To investigate the effects of Hemorrheological factors and related trace elements on oral recurrent aphthae ulcer （RAU）. Methods：Selected 83 patients with RAU from volunteer blood donors. Detected the Hemorrheological indicators and the contents of Mg , Fe , Zn , Se and Cu. Comparative Analysised them with healthy volunteers. Results ： The patients with RAU’s levels of whole blood viscosity , whole blood reduced viscosity , plasma viscosity and hematocrit are higher than the control one （ P0.05 ） .Erythrocyte electrophoresis time is prolonged , and erythrocyte sedimentation rate is dropped （ P0.05 ） .The contents of Zn and Se are lower than the control one （ P0.05 ） . However , there is no statistical significance about the contents of Mg , Fe and Cu between the two groups （ P0.05 ） . Conclusion ： Patients with RAU may be lack of Zn and Se.Furthermore , there are changes of Hemorrheological circumstances.This research provide references for the clinical treatments of RAU by means of improving blood circulation or supplement Zn and Se rationally.

关 键 词：复发性阿弗他溃疡 血液流变学 微量元素 

分 类 号：R781.5[医药卫生—口腔医学]