脑卒中急性期抑郁焦虑共病的临床特点研究  

Factors Related to Post-stroke Comorbid Anxiety

作　　者：陆学胜[1] 许敏[1] 张燕[1] 姚胜旗[1] 张允[1] 

机构地区：[1]上海市长宁区中心医院神经内科,上海200336

出　　处：《神经损伤与功能重建》2010年第6期417-421,共5页Neural Injury and Functional Reconstruction

摘　　要：目的：研究卒中后抑郁焦虑共病（PSCAD）的发生率、临床特征及影响因素.方法：选择2007年5月～2008年12月我科符合入组标准的急性期脑卒中住院患者246例,应用汉密顿焦虑量表（HAMA）和汉密顿抑郁量表（HAMD）,结合CCMD-3诊断标准,采用χ2检验、t检验、Logistic回归分析,评价卒中后第2周PSCAD的临床特点.结果：PSCAD发病66例（26.83%） 神经功能缺损程度是PSCAD的危险因素,社会支持是PSCAD的保护因素 应付方式中积极应付方式分值越高,患PSCAD的危险性越小,消极应付方式分值越高,患PSCAD的危险性越大 既往焦虑史、病灶数量与PSCAD患病风险呈正相关.结论：PSCAD与既往焦虑史、病灶数量、神经功能缺损程度、社会支持及应付方式密切相关.Objective：To analysis the incidence rate, clinical characteristics and associated factors of post-stroke comorbid anxiety and depression （PSCAD）. Methods： Two hundred and forty-six patients with acute stroke have been studied. Hamilton Anxiety Scale （HAMA）, Ham- ilton Depressive Scale （HAMD） and CCMD-3 were used to assess the incidence rate of PSCAD at two weeks after stroke. In the univariate analysis, the X2 method for categorical variables and t test for continuous variables were used and the unconditional Logistic regression were used to an- alyze the relationships between the incidence of PSCAD and associated factors. Results-The inci- dent rate of PSCAD was 26. 830//00 （66/246）. The serious neurologic impairment, passive coping style, the history of anxiety and multifocal infarction were the risk factors for PSCAD. The social support and positive coping style were the protective factors of PSCAD. Conclusion： The past history of anxiety, number of lesions, severity of neurologic impairment, social support and the coping style are important factors related to the incidence of PSCAD.

关 键 词：卒中后抑郁焦虑共病 神经功能缺损 社会支持 应付方式 

分 类 号：R743[医药卫生—神经病学与精神病学] R749.7[医药卫生—临床医学]