药物治疗干眼症的对比研究  

Contrast study of drug therapy for dry eye

作　　者：杜红艳[1] 李兰根[1] 杜鹏程[2] 钱志敏[1] 王中颖[1] 

机构地区：[1]内蒙古自治区医院眼科 [2]包头医学院第一附属医院眼科,中国内蒙古自治区包头市010014

出　　处：《国际眼科杂志》2010年第12期2361-2362,共2页International Eye Science

摘　　要：目的:观察贝复舒滴眼液联合泪然滴眼液对干眼症的疗效。方法:将134例干眼症患者随机分为试验组(69例)和对照组(65例),试验组应用泪然滴眼液联合贝复舒滴眼液,各4次/d,连用1mo;对照组应用泪然滴眼液,4次/d,连用1mo。分别做基础泪液分泌试验(SⅠt)、泪膜破裂时间检查(BUT),对结果进行统计学分析。结果:两组用药前SⅠt,BUT无显著性差异(P>0.05),治疗后,两组SⅠt,BUT均有统计学意义(P<0.01),试验组治疗前后SⅠt,BUT结果比较有统计学意义(P<0.01)。结论:贝复舒滴眼液联合泪然滴眼液对干眼症有良好的效果。AIM：To evaluate the effects of basic fibroblast growth factor（bFGF） combined with nature tears Ⅱ in the treatment of dry eye. METHODS：Totally 134 patients with dry eye were randomly divided into experiment group（69 eyes） treated by basic fibroblast growth factor combined with nature tears Ⅱ and control group（65 eyes）treated by nature tears Ⅱ with four times every day. The Schimer Ⅰ test（SⅠt）, tear film break up time（BUT）were compared with before and one month later in both groups. The results were analysed statistically. RESULTS：There were significant difference in SⅠt and BUT one month after treatment in both groups （P〈0.01） whereas no difference before the treatment（P〉0.05）.There were significant difference in SⅠt and BUT in experiment group before and one month later （P〈0.01）. CONCLUSION：bFGF combined with nature tears Ⅱ is an effective method for dry eye.

关 键 词：干眼/药物治疗 碱性成纤维细胞生长因子 泪然 

分 类 号：R777[医药卫生—眼科]