C-myc与非霍奇金淋巴瘤的关系研究进展  

Research on the relationship between the C-myc and non-Hodgkin,s lymphoma

作　　者：王京琼[1] 孟丹[1] 

机构地区：[1]宁波大学医学院,浙江宁波315211

出　　处：《现代肿瘤医学》2010年第12期2489-2491,共3页Journal of Modern Oncology

基　　金：宁波市科学技术局资助项目(编号:2005C100118)

摘　　要：非霍奇金淋巴瘤(NHL)是全球发病率最高的五大肿瘤之一,近年来发病率呈明显上升趋势。原癌基因C-myc在基因转录调控机制中发挥着重要作用,与NHL的发生、发展和演变转归有重要关系。将C-myc基因作为NHL的研究重点,能够使我们对NHL的发病机制有进一步的了解,为NHL分型、预后判断和制定治疗方案等提供可靠的理论依据。Non-Hodgkin＇s lymphoma（NHL） is one of the five most common cancer in the world,in recent years,its incidence has clearly been an upward trend.Proto-oncogene C-myc plays an important role in gene regulation mechanism of transcription,closely related to NHL＇s occurrence,development and evolution.C-myc gene study of NHL can give us a better understanding of pathogenesis,and provide a reliable theoretical basis for the NHL＇s sub-type,prognosis and the development of treatment programs.

关 键 词：C-MYC 非霍奇金淋巴瘤 基因重排 临床诊断 预后 

分 类 号：R730.3[医药卫生—肿瘤]