腹腔灌注和全身热疗治疗非根治术后晚期胃癌56例临床分析  

Observation on intraperitoneal chemotherapy combined with whole body hyperthermia after palliative surgery for advanced gastric carcinoma

作　　者：夏春芳[1] 潘友兰[1] 黎静[1] 杜颖[1] 雷俊[2] 

机构地区：[1]中南大学湘雅二医院肿瘤中心,湖南长沙410011 [2]中南大学湘雅三医院,湖南长沙410013

出　　处：《中国现代医学杂志》2010年第3期461-463,466,共4页China Journal of Modern Medicine

摘　　要：目的探讨腹腔灌注和全身热疗治疗非根治术后晚期胃癌的疗效。方法56例非根治术后晚期胃癌患者随机分为两组:对照组和热疗组。每组28例,对照组予腹腔灌注化疗+全身化疗;热疗组在对照组基础上,腹腔灌注后予全身热疗。结果热疗组的2年生存率明显高于对照组(P<0.05)。两组间毒副作用差异无显著性。结论腹腔灌注和全身热疗治疗非根治术后晚期胃癌是一种有效的治疗手段。【Objective】To evaluate the curative effect of intraperitoneal chemotherapy combined with whole body hyperthermia after palliative surgery for advanced gastric carcinoma.【Methods】 A total of 56 patients with advanced gastric cancer who underwent non-radical surgery were randomly divided into two groups（n=28 in each group）,i.e.control group and thermotherapy group.The control group was treated with intraperitoneal chemotherapy and body chemotherapy while the thermotherapy group was treated with whole body hyperthermia after intraperi-toneal chemotherapy,and the remaining treatments were the same with the control group.【Results】The rate of 2 year survival had significant difference between the two groups,it was higher in the thermotherapy group than in the control group（P〈0.05）,and the side effects between the two groups had no significant difference.【Conclusion】It is a useful method to treat patients who have accepted palliative surgery for advanced gastric carcinoma with intraperitoneal chemotherapy combined with whole body hyperthermia.

关 键 词：腹腔灌注 全身热疗 胃癌 非根治术 

分 类 号：R735.2[医药卫生—肿瘤] R454.5[医药卫生—临床医学]