晚发性精神分裂症的磁共振对照研究  

MRI changes in late onset schizophrenia compared to normal controls

作　　者：李海林[1] 吕耀娟[1] 叶勤[1] 李惠国[1] 陈晔[1] 计庆明[1] 

机构地区：[1]南京医科大学附属脑科医院

出　　处：《临床精神医学杂志》1999年第2期81-82,共2页Journal of Clinical Psychiatry

摘　　要：目的：了解晚发性精神分裂症患者脑磁共振的变化特征。方法：选择１７例晚发性精神分裂症病人，和正常对照组１７例检测脑的磁共振，以第三脑室宽距，侧脑室间距，侧脑室体部最大间距，左、右颞角宽度，额叶脑沟宽度及顶叶脑沟宽度为观察点。结果：发现病例组异常率为５２．９４％，海马异常率为４１．１８％，与正常对照组相比，第三脑室、左颞角宽度、额叶脑沟宽度和顶叶脑沟宽度有显著差异。结论：晚发性精神分裂症病人的海马、左颞叶、额叶和顶叶有脑结构改变。Objective:To compare the findings between late onset schizophrenic patients and normal controls. Method:17 patients with late onset schizophrenia and 17 normal subjects were studied with MRI of brain. Results:An overall 52 94% of structural abnormality was found in the schizophrenic subjects,hippocampal formation infarction were 41 18%.There were significant differe nces in the width of the third ventricles,fissure of frontal lobe,left horn of temporal,frontal lobe,parietal lobe between late onset schizophrenia and normal controls. Conclusion:There are structure variance in the hippocampal,left temporal lobe,frontal lobe and parietal lobe of late onset schizophrenia.

关 键 词：晚发性 精神分裂症 脑结构 NMR 成像 

分 类 号：R749.304[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]