3-苄基-5-溴脲嘧啶类化合物的合成及除草活性  

Synthesis and Herbicidal Activity of 3-Benzyl-5-Bromouracil Derivatives

作　　者：李公春[1] 朱有全[2] 杨风岭[1] 杨华铮[2] 

机构地区：[1]许昌学院化学化工学院,河南许昌461000 [2]南开大学元素有机化学研究所元素有机化学国家重点实验室,天津300071

出　　处：《安徽农业科学》2010年第33期18920-18921,共2页Journal of Anhui Agricultural Sciences

基　　金：河南省自然科学基金资助项目(082300420110);河南省教育厅自然科学基金资助项目(2007150036)

摘　　要：[目的]研究3-苄基-5-溴脲嘧啶类化合物的除草活性。[方法]3-苄基脲嘧啶类化合物与溴化锂、硝酸铈铵在乙腈作溶剂条件下回流反应,尿嘧啶环上5位氢原子被溴原子取代。[结果]合成了5个3-苄基-5-溴脲嘧啶类化合物,所有目标化合物均通过1H NMR确证。[结论]该类化合物有一定的除草活性,其中化合物c浓度100 mg/L时对油菜根长生长抑制具有较好的效果。[Objective] The study aimed to explore herbicidal activities of 3-benzyl-5-bromouracil derivatives.[Method] 3-benzyluracil derivatives reacted with lithium bromide and ammonium ceric nitrate.5-position hydrogen of uracil ring was substituted by bromide atom.[Result] Five 3-benzyl-5-bromouracil derivatives were synthesized,and all compounds were confirmed by 1H NMR.[Conclusion] The herbicidal activities of these compounds were examined.The biological test results showed that compound c had good activities against Brassica napus at 100 mg/L.

关 键 词：3-苄基-5-溴脲嘧啶 合成 除草活性 

分 类 号：O626.4[理学—有机化学]