酸浆化学成分研究(Ⅱ)  

Chemical constituents of Physalis alkekengivar. franchetii(Ⅱ)

作　　者：袁野[1] 许枬[1] 步显坤[1] 战宏利[1] 张萌萌[1] 

机构地区：[1]辽宁中医药大学,辽宁大连116600

出　　处：《中草药》2010年第12期1939-1942,共4页Chinese Traditional and Herbal Drugs

基　　金：科技部基础平台项目(2005DKA21004)

摘　　要：目的研究酸浆Physalis alkekengivar.franchetii宿萼内活性成分。方法采用硅胶、凝胶、高效液相等色谱技术分离,利用理化性质和核磁共振光谱、MS等技术鉴定结构。结果分离得到4个化合物,分别为反式咖啡酸乙酯(1)、25,27-二脱氢酸浆苦素L(2)、酸浆苦素D(3)、大血藤苷E(cuneataside E,4)。结论化合物2为新的天然产物,化合物4为首次从该植物中分离得到。Objective To investigate the chemical constituents in persistent calyx of Physalis alkekengi var.franchetii.Methods Various colume chromatographies over silica gel,Sephadex LH-20,and HPLC were used to separate the chemical constituents and their structures were elucidated by physicochemical property,1H-NMR,13C-NMR,and MS.Results Four chemical constituents were obtained and identified as caffeic acid ethyl ester（1）,25,27-dehydro-physalin L（2）,physalin D（3）,and cuneataside E（4）.Conclusion Compound 2 is a new natural product,and compound 4 is isolated from the plant for the first time.

关 键 词：酸浆 酸浆苦素D 25 27-二脱氢酸浆苦素L cuneataside E 

分 类 号：R284.1[医药卫生—中药学]