立体定向放射治疗胰腺癌的疗效分析  

Clinical analysis of stereotactic conformal radiotherapy for patients with pancreatic carcinoma

作　　者：季洪兵[1] 吕光明[1] 钟南保[1] 陈忠华[1] 

机构地区：[1]南京军区福州总医院肿瘤放射治疗中心,福州市350025

出　　处：《实用肝脏病杂志》2010年第6期436-437,440,共3页Journal of Practical Hepatology

摘　　要：目的探讨立体定向放疗(体部伽玛刀)治疗胰腺癌的疗效。方法采用立体定向放射治疗58例胰腺癌患者,给予等剂量曲线50%～90%,周边照射总剂量3000～4800 cGy,分割处方剂量300～600cGy,重复治疗10～15次。结果 58例胰腺癌患者在治疗后3个月,完全缓解5例(8.6%),部分缓解22例(37.9%),稳定25例(43.1%),进展6例(10.3%)。1年生存率为62.2%。结论立体定向放疗治疗胰腺癌,安全有效,可以提高患者的生存期。Objective To evaluate clinical therapeutic effecttiveness of stereotactic conformal radiotherapy（body gamma knife）for patients with pancreatic carcinoma.Methods 58 patients with pancreatic carcinoma were treated with stereotactic conformal radiotherapy.Planning target volume received 50%～90% of the prescribed dose for 3～6Gy per fraction.The total doses in tumor margins were 30～48Gy.The therapy was repeated one time each day for 10～15times.Results In the 58 patients,CR was 8.6%,PR 37.9%,NC 43.1% and PD 10.3%,with a total response rate of 46.6% at three months after treatment.The 1-yr survival rates of patients were 62.2%.Conclusion The stereotactic conformal radiotherapy technique is a safe and effective treatment for patients with pancreatic carcinoma.

关 键 词：胰腺癌 立体定向放射治疗 近期疗效 

分 类 号：R735.9[医药卫生—肿瘤]