原发性腹膜后恶性肿瘤249例临床研究  

A clinical study of 249 cases of malignant Primary Retroperitoneal Tumor

作　　者：徐果[1] 彭正[2] 

机构地区：[1]江苏省淮安市第一人民医院普外科,223300 [2]解放军总医院普外科,北京100853

出　　处：《重庆医学》2010年第23期3246-3247,3249,共3页Chongqing medicine

摘　　要：目的总结恶性原发性腹膜后肿瘤（PRPT）临床治疗经验,分析影响术后效果的因素。方法回顾性分析解放军总医院1999-2008年收治的249例恶性PRPT的临床资料。结果 249例共手术302例次,肿瘤完全切除176例次。恶性PRPT完全切除患者的1、3、5年生存率分别为89.4%、73.7%、55.3%（P〈0.01）,部分切除患者的1、3、5年生存率分别为72.3%、34.5%、5.9%（P〈0.01）。肿瘤是否完全切除、肿瘤大小、部位、肿瘤分化等级是影响肿瘤复发和生存期的重要因素（P〈0.01）。结论充分做好手术前准备,提高肿瘤完全切除率,是降低肿瘤复发,提高生存率的关键。Objective To summarize the experience of management for malignant primary retroperitoneal tumor（PRPT）and analyze the factors influencing the effect after operation.Methods We analysed 249 patients with malignant primary retroperitoneal tumor in PLA general hospital during the 1999～2008 according to the clinical information.Results 230 cases were surgically treated,the number of operations were 302,and of which the totally tumorectomy were 176 cases.The 1,3,and 5 year survival rates in complete resection Patients were 89.4%、73.7%、55.3% respectively（P〈0.01）,and those in incomplete resection patients were 72.3%、34.5%、5.9% respectively（P〈0.01）.The Cox multi-various regression analysis showed that incomplete tumor resection,size of tumor,position and histological grade were associated with local recurrence and surviva1.Conclusion Sufficient pre-operative preparation.and complete tumor resection are important roles for reducing recurrence and improving surviva1.

关 键 词：腹膜后肿瘤 恶性 联合脏器切除 生存率 

分 类 号：R735.4[医药卫生—肿瘤] R730.56[医药卫生—临床医学]