单鼻孔入路垂体腺瘤切除术后并发症及死亡原因分析  

Analysis of Death Causation and Complicating Disease on Resecting Pituitary Adenoma by Microsurgery through Endonasal Transsphenoidal Approach

作　　者：程建业[1] 樊丰势[1] 齐洪武[1] 张旭东[1] 张卫宁[1] 赵亚鹏[1] 刘艳宁[1] 

机构地区：[1]中国人民解放军白求恩国际和平医院神经外科,石家庄市050082

出　　处：《医药论坛杂志》2010年第20期31-33,共3页Journal of Medical Forum

摘　　要：目的探讨经单鼻孔入路垂体腺瘤切除手术、术后并发症及死亡原因。方法对136例垂体瘤患者行单鼻孔入路垂体腺瘤切除术并分析其疗效、术后并发症及死亡原因。结果肿瘤全切89例(65.4%),次全切除46例(33.8%),因术中大出血未行手术切除1例。术后出现并发症16例(11.8%),死亡4例(2.9%)。结论单鼻孔入路切除垂体腺瘤有手术时间短,创伤小,并发症少等优点。但仍有诸多因素可导致术后并发症甚至死亡,因此我们必须做好术前评估,选择合适的手术适应症,进行个体化手术设计,掌握局部显微解剖,娴熟手术技巧,严密术后观察。Objective To study the death causation and complicating disease of resecting pi-tuitary adenoma by microsurgery through endonasal transsphenoidal approach.Methods The clinical data of 136 patients with pituitary adenoma were retrospectively analyzed.All patients underwent mi-crosurgery through endonasal transsphenoidal approach.Results The tumors were totally removed in 89（65.4%） patients and subtotally in 46（33.8%）,1 case without resection because of intraoperative hemorrhage,16 cases（11.8%） had postoperative complications,4 cases died（the mortality was2.9%）.Conclusion This microsurgical operation has merits such as minimal invasions,hort oper-ative timef,ew complications.But there are many factors can cause postoperative complications and death.So we should do preoperative evaluationc,hoose the proper operation indcation,designated oper-ation plan for every special patient,grasp opography and microdissection,grasp skilled micromanipula-tion and ensure rigorous postoperative observation.

关 键 词：垂体腺瘤 神经内镜 经单鼻孔-蝶窦入路 术后并发症 死亡因素 

分 类 号：R736.4[医药卫生—肿瘤]