抗利尿激素分泌不当综合征15例临床分析  

Syndrome of inappropriate secretion of antidiuretic hormone on 15 cases

作　　者：范文强[1] 

机构地区：[1]河南省焦作市第二人民医院,454001

出　　处：《中国医学创新》2010年第35期109-110,共2页Medical Innovation of China

摘　　要：目的增强对抗利尿激素分泌不当综合征(SIADH)的认识,提高对本综合征的诊治水平。方法通过对15例SIADH患者临床表现、化验检查结果及治疗及预后情况等临床资料进行分析。结果引起SIADH的基础疾病多种多样,最常见为肿瘤和肺部炎症,其临床症状和体征无特异性,实验室检查均有低钠血症,低血浆渗透压和高尿渗透压,病情的轻重与血钠水平相关,预后与原发病能否根治有关。结论 SIADH临床上并不少见,其临床表现无特异性,极易造成误诊、漏诊,化验血钠、血尿渗透压是诊断SIADH的主要依据,早诊断、早治疗是提高救治成功率的关键,治疗上限水、利尿比补钠更重要。Objective To enhance our knowledge of Syndrome of inappropriate secretion of antidiuretic hormone（SIADH） ,improve the diagnosis and treatment level. Methods Analysis the clinical data as clinical manlfestations,inspection results,treatment and prognosis situation of 15 patients with SIADH. Results The cause of SIADH is various,tumor and lung inflammation is most common, the clinical symptoms is atypital, all of them got hyponatremia,low plasma osmotic pressure and high urinary osmotic pressure. The symptoms negatively correlated with serum sodium levels, and the prognosis dependent on whether the protopathy can be cured. Conclusion SIADH is not rare, the clinical symptoms is atypital, easily mistaken and misdiagnosis. Serum sodium,plasma osmotic pressure and urinary osmotic pressure is the evidence of diagnosis. Early diagnosis and early treatment is the key to improve the treatment efficacy,water rationing, diuresis is more important than fill sodium.

关 键 词：抗利尿激素分泌不当综合征 低钠血症 

分 类 号：R730.6[医药卫生—肿瘤]