慢性酒精中毒性肌病的临床及病理特点研究  

作　　者：赵清石[1] 鞠浩[1] 刘海燕[1] 刘川[1] 

机构地区：[1]北华大学附属医院神经内科,132001

出　　处：《当代医学》2010年第34期58-59,共2页Contemporary Medicine

摘　　要：目的探讨慢性酒精中毒性肌病患者的临床表现、骨骼肌活检病理特点。方法总结12例临床确诊的酒精中毒性肌病患者的临床资料,对确诊病例行骨骼肌活检,行组织化学染色,光镜下观察、摄片,进行病理分析。结果慢性酒精中毒肌病患者以肌无力、肌萎缩为主要表现,辅助检查无明显特异性;肌肉病理可见坏死、萎缩肌纤维,以Ⅱ型肌纤维萎缩为主,可见不整红边纤维(RRF)。结论慢性酒精中毒性肌病的病理变化多样,综合病史、病理检查,完善相关辅助检查是诊断该病的关键。Objective To investigate clinical manifestations and pathological features of patients with chronic alcoholic myopathy. Methods Summary clinical data of 12 cases with clinically diagnosed chronic alcoholic myopathy,skeletal muscle biopsy to final diagnosis cases and histochemica stain,observed in light microscopy and photographed,for pathological analysis. Results The main clinical manifestations of patients with chronic alcoholic myopathy are muscle weakness,muscle atrophy,and no specificity. In muscle pathology ,necrosis and atrophy of muscle fibers were observed,and muscle fiber atrophy type ,RRF were found in some muscle fibers. Conclusion Various pathological changes were found in chronic alcoholic myopathy. It is the key that comprehensive medical history,muscle pathology,and the relevant auxiliary examination were used.

关 键 词：酒精中毒 肌病 骨骼肌活检 病理 

分 类 号：R747.9[医药卫生—神经病学与精神病学]