前列地尔联合异甘草酸镁治疗肝硬化活动期疗效观察  

Observation on clinical therapeutic effect of Alprostadil combined with Magnesium Isoglycyrrhizinate on patients with Hepatocirrhosis at active phase

作　　者：李宏[1] 何媛[1] 韦明[1] 何锐[1] 

机构地区：[1]马鞍山市传染病医院肝病科,安徽省马鞍山243031

出　　处：《中国基层医药》2010年第22期3068-3069,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的观察前列地尔联合异甘草酸镁治疗肝硬化活动期的临床疗效。方法选择住院患者74例，随机分为治疗组37例和对照组37例。对照组给予常规保肝的对症治疗。治疗组在常规保肝对症治疗的基础上加用前列地尔和异甘草酸镁，每天一次，静脉滴注，疗程为4周，观察临床效果。结果治疗组总有效率67．6％，对照组总有效率40．5％，两组比较差异有统计学意义（P〈0．05）。结论联合使用前列地尔和异甘草酸镁治疗肝硬化活动期有较好疗效。Objective To evaluate the effect of Alprostadil combined with Magnesium Isoglycyrrhizinate on hepatocirrhosis at active phase. Method 74 inpatients collected from our hospital were randomly divided into control group （37 cases ）and treatment group （37 cases）. The patients in control group were given conventional liver protecting treatment. In addition to routine therapy of the control group, the patients in treatment group received intravenous Alprostadil and Magnesium Isoglycyrrhizinate injection once a day for 4 weeks. Results The total effective rate of treatment group was 67. 6% , and that of control group was 40. 5%, and the difference was significant （ P 〈 0. 05 ）. Conclusion Alprostadil combined with Magnesium Isoglycyrrhizinate has good clinical therapeutic effect on hepatocirrhosis at active phase.

关 键 词：前列地尔 甘草酸 肝硬化 

分 类 号：R575[医药卫生—消化系统]