膀胱内翻性乳头状瘤的诊断与治疗(附12例报告)  

Diagnosis and treatment of inverted papilloma of bladder (A report of 12 cases)

作　　者：刘忠国[1] 顾艳枝[1] 匡蕾[1] 王甡[1] 王鹏举[1] 徐涛[1] 

机构地区：[1]青岛大学医学院第二附属医院泌尿外科,山东青岛266042

出　　处：《实用肿瘤杂志》2010年第6期674-676,共3页Journal of Practical Oncology

摘　　要：目的提高膀胱内翻性乳头状瘤(inverted papilloma of the bladder,IPB)的诊治水平。方法回顾性分析我院12例膀胱内翻性乳头状瘤患者的临床资料,结合文献资料进行探讨。结果 12例患者接受经尿道膀胱肿瘤电切术(TURBt)治疗,患者术后均恢复良好,无严重并发症。4例伴有前列腺增生者,同时行TURP术,术后排尿良好。术后病理明确诊断为膀胱内翻性乳头状瘤,其中小梁型9例、腺体型3例。4例同时行TURP者,术后前列腺组织病理为良性前列腺增生。术后均给予膀胱灌注化疗。术后随访6月-8年,未见肿瘤复发及恶性变。结论 IPB多见于男性,膀胱颈部和三角区多发,呈良性肿瘤特点生长,预后良好。诊断依赖于膀胱镜检查及术后病理检查。TURBt是IPB的标准治疗方法 ,术后给予膀胱灌注化疗有利于预防复发。Objective To improve the levels of diagnosis and treatment of inverted papilloma of the bladder（IPB）.Methods Data of 12 cases with IPB were analyzed retrospectively and discussed with reference to the literature.Results All of the 12 patients received transurethral resection of bladder tumor（TURBt）.They recovered well and no complication occurred after operation.At the same time,4 cases with benign prostatic hyperplasia（BPH） were underwent transurethral resection of prostate（TURP） and they urinated well after operation.All cases were diagnosed as IPB confirmed by pathology after operation,including 9 cases of trabecular type and 3 of glandular type.Four cases with TURP were diagnosed as BPH in pathology.All cases were underwent bladder irrigation chemotherapy.No recurrence or malignant change during the follow-up period from 6 months to 8 years were observed.Conclusion IPB is common in male and situated at bladder neck or trigone,which is a benign tumor with good prognosis.Cystoscopic examination and postoperative pathologic examination are the most important confirmed diagnostic method.TURBt is the standard treatment to IPB.Intravesical instillation with chemotheraputic drugs after initial operation is beneficial to prevent recurrence.

关 键 词：膀胱肿瘤/诊断 膀胱肿瘤/治疗 灌注 局部 投药 膀胱内 乳头状瘤 内翻/诊断 乳头状瘤 内翻/治疗 

分 类 号：R737.14[医药卫生—肿瘤]