超声造影鉴别诊断原发性小肝癌与肝硬化再生结节的应用研究  

Early Diagnosis of Small Hepatocellular Carcinoma by Contrast-enhanced Ultrasound

作　　者：徐金锋[1] 施杨[1] 罗慧[1] 冯晓凤[1] 丁志敏[1] 吴瑛[1] 

机构地区：[1]暨南大学第二临床学院,深圳市人民医院超声科,广东省深圳市518020

出　　处：《中国超声医学杂志》2010年第12期1095-1098,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的研究超声造影鉴别原发性小肝癌和肝硬化再生结节有意义的参数,提高早期诊断小肝癌的准确率。方法对45个小肝癌病灶和41个肝硬化再生结节病灶行超声造影检查及ACQ时间强度曲线分析,获得每个病灶造影相关参数及时间-强度曲线的集中、离散趋势[中位数(Median)和四分位数(Quartile range,QR)]。结果小肝癌组和肝硬化再生结节组间增强斜率和中位数有显著统计学差异,而到达时间、达峰时间、四分位数无显著统计学差异。结论增强斜率和中位数可用于鉴别小肝癌和肝硬化再生结节,提高早期诊断小肝癌的准确率。Objective To explore the significant parameters to differentiate small hepatocellular carcinoma and hepatocirrhosis regenerative nodule,in order to improve the accuracy of early small hepatocellular carcinoma diagnosis. Methods 45 small hepatocellular carcinomas and 41 regenerative nodules were included. After contrast-enhanced ultrasound（CEUS） ,ACQ was used to analyse the arrive time（AT）, time to peak（TTP）, peak intensity（PI）, enhancement slope,median and quartile range（QR）. Results According to contrast administration, AT, TTP and QR showed no significant statistics difference, while PI, enhancement slope and median were of highly statistic significance. Conclusions PI, enhancement slope and median. They can be used to differentiate small hepatocellular carcinoma and regenerative nodule by CEUS,and diagnose small hepatocellular carcinoma as early as possible.

关 键 词：超声造影 小肝癌 时间-强度曲线 集中趋势 离散趋势 

分 类 号：R735.7[医药卫生—肿瘤] R445.1[医药卫生—临床医学] R575.2