肛周HPV18阳性鲍温病1例  

A Case of Perianal Bowen Disease with Infection of HPV18

作　　者：张跃[1] 罗丽[1] 袁伟[1] 

机构地区：[1]遵义医学院附属医院皮肤科,贵州遵义563003

出　　处：《中国皮肤性病学杂志》2010年第12期1145-1146,共2页The Chinese Journal of Dermatovenereology

基　　金：贵州省科学技术基金(黔科合J字[2005]2060号);贵州省优秀青年人才基金(省卫生厅D-241)

摘　　要：患者男,58岁,肛周红斑,逐渐隆起,伴糜烂、渗液、疼痛1年。肛周见一类圆形暗红色斑块,边界清楚,大部分不规则隆起,部分疣状增生,呈鲜红色,表面湿润,少许糜烂。触之较硬。皮损处活检组织病理示:肛周原位鳞状细胞癌(鲍温病)。人乳头状瘤病毒分型检测:HPV18阳性。治疗:广泛的病灶切除。A 58-year-old man presented with a red and raised plaque around anus,with erosion,exudations and pain for 1 year. The lesions appeared sharply circumscribed plaque. Most of it raised irregularly,some area showed verrucous hyperplasia. The surface had a little secretions and erosion. It was hard fairly to touch. Histopathology showed squamous cell carcinoma in situ （Bowen＇s disease）. Detection of human papillomavirus showed HPV 18 was positive. The patient underwent wide local excision.

关 键 词：鲍温病 肛周 HPV18 

分 类 号：R739.5[医药卫生—肿瘤]