氦氖激光血管内照射对脑梗塞患者红细胞变形性和Na^+-K^+-ATP酶的影响  

Effect of intravascular He-Ne laser irradiation on blood for erythrocyte deformity and erythrocyte membrane Na+-K+ATPase in acute cerebral infarction patients

作　　者：许贞峰[1] 辛平[1] 金丽英[1] 杨学伟[1] 石秉霞[1] 

机构地区：[1]青岛大学医学院脑血管病研究所

出　　处：《中华理疗杂志》1999年第3期141-142,共2页Chinese Journal of Physical Therapy

摘　　要：目的：观察低能量氦氖激光血管内照射（ＩＬＩＢ）对脑梗塞患者红细胞变形性和红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶的影响。方法：４６例脑梗塞患者应用ＩＬＩＢ治疗，每日１次，１０分钟；对照组４２例单纯药物治疗。检测健康人、急性脑梗塞患者单纯药物治疗组及ＩＬＩＢ治疗组治疗前后红细胞变形性和红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶，并进行对照分析。结果：急性脑梗塞患者红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性和红细胞变形性明显低于正常对照组，单纯药物治疗组治疗后酶活性及红细胞变形性提高，但差异无显著性（Ｐ＞０．０５），ＩＬＩＢ治疗组治疗１０次后Ｎａ＋－Ｋ＋－ＡＴＰ酶活性及红细胞变形性明显提高，分别为０．１９８±０．１１，０．３８９±０．０９１，与治疗前０．１３１±０．０７，０．３３６±０．０１０比较，差异有非常显著性（Ｐ＜０．０１）。结论：ＩＬＩＢ是治疗脑梗塞改善微循环障碍一种有效辅助疗法。Objective: In order to observe the effect of intravascular He-Ne laser irradiation on blood(ILIB) for erythrocyte deformity and its membrane Na+-K+-ATPase activity of acute cerebral infarction(ACI) patients. Methods: 46 cases with ACI were treated with ILIB,once a day ,for 10 times. Another 42 cases as control group were only received the drug treatment.Before and after treatment,the erythrocyte deformity and membrane Na+-K+-ATPase activity were analysed and compared in both groups.While the above parameters of 25 healthy persons were detected too. Results: The study found that erythrocyte deformity and membrane Na+-K+-ATPase activity of ACI patients was obviously lower than the healthy persons.After ILIB 10 treatments,the above indexes of ACI patients were markedly increased 0.1980.11 and 0.3890.091 compared with the pre-ILIB treatment 0.310.07 and 0.3360.010( P<0.01). Of control gronp,there wasn't significant difference at pre- and post-treatment( P>0.05). Conclusion:ZIt is indicated that ILIB could enhence the erythrocyte deformability and Na+-K+-ATPase activity.It may improve the cerebral microcirculation.So it is an effective and cooperative therapy for ACI patients.

关 键 词：红细胞变形性 ATP酶 脑梗塞 激光疗法 ILIB 

分 类 号：R743.440.5[医药卫生—神经病学与精神病学] R454.2[医药卫生—临床医学]