神经白塞病36例临床分析  

Clinical analysis of thirty-six Neuro-Behcet' disease cases

作　　者：徐佳亮[1] 赵久晗[2] 付峻[1] 牛英翔[1] 魏艳花[1] 陈晓虹[1] 

机构地区：[1]辽宁省人民医院神经内六科,辽宁沈阳110001 [2]中国医科大学第一医院神经内科,辽宁沈阳110001

出　　处：《中风与神经疾病杂志》2010年第11期1007-1009,共3页Journal of Apoplexy and Nervous Diseases

摘　　要：目的系统性评价神经白塞病的临床表现,脑脊液(CSF)结果和磁共振(MRI)特征。方法对36例神经白塞病患者的临床表现、CSF检查结果和影像学特征进行回顾性分析。结果纳入研究的神经白塞病,男∶女=1.27∶1,神经白塞病出现在白塞病发病后的8个月～12年(平均4年)。锥体束损害是神经白塞病最常见的神经系统症状,发生率达41.7%;36例中实质型为25例(脑实质型23例、脊髓实质型2例),颅内高压型4例,混合型3例,其他类型4例。结论中枢神经系统实质型是我国神经白塞病的主要表现形式,CSF和MRI检查不仅是提高神经白塞病检出率和对其分型的有效手段,而且是判断神经白塞病活动性的可靠指标。Objective To evaluate Neuro-Behcet＇s disease（NBD）clinical manifestations,cerebrospinal fluid（CSF）results and magnetic resonance（MRI）features.Methods 36 cases of NBD clinical manifestations,CSF findings and imaging features were retrospectively analyzed.Results Neurological involvement occurred after the onset of Behcet＇s disease（BD）from eight months to twelve years（average four years）with male∶female=1.27∶1.The most common form of NBD nervous system damage was pyramidal tract damage,and the incidence reached 41.7%.There were 25 CNS parenchymal type cases（22 brain parenchymal cases,3 spinal cord parenchyma cases）,4 intracranial hypertension type cases,3 mixed type cases,and 4 other type cases.Conclusions CNS parenchymal type is the major manifestation of NBD in China.CSF and MRI examination is not only the effective means of NBD detection and classification,but also the indicator to determine NBD activity.

关 键 词：神经白塞病 脑脊液 磁共振 

分 类 号：R743[医药卫生—神经病学与精神病学]