介入化疗栓塞治疗32例宫颈癌合并出血的临床疗效分析  

Interventional Chemotherapy and Embolization for Persistent Bleeding with Carcinoma of Uterine Cervix

作　　者：赵玉年[1] 林厚斌[1] 崔怀萍[1] 徐向红[1] 张晓[1] 王慧华[1] 吴建达[1] 

机构地区：[1]江苏省肿瘤医院放射科

出　　处：《南京医科大学学报（自然科学版）》1999年第4期309-311,共3页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏省科委应用基础科研项目

摘　　要：目的探讨介入化疗栓塞治疗宫颈癌合并出血的临床意义。方法对３２例宫颈癌合并出血的患者采用子宫动脉灌注５－氟尿嘧啶（５－Ｆｕ）、顺铂（ＰＤＤ）、丝裂霉素（ＭＭＣ）加碘油行子宫动脉化疗栓塞，再用明胶海绵栓塞止血。结果①盆腔动脉造影能清楚显示肿瘤血管及范围，明确出血部位，经化疗栓塞后全部病例得以止血。②介入治疗能够短时间内控制巨大肿瘤，但难以使肿瘤完全坏死。结论介入化疗栓塞能够取得满意的止血效果，是其他治疗手段不可比拟的。介入治疗能够提高宫颈癌的近期疗效，但单纯用介入治疗难以根治，必须配合手术治疗或放射治疗。Objective\ To evaluate the clinical efficacy of intervention chemotherapy and embolization in the treatment of persistent bleeding with cervical cancer. Methods\ 32 patients were treated by uterine artery infusion of 5 Fu, PDD, MMC chemotherapy and embolization with lipiodol and gelfoam. Results\ ① Pelvic arteriography shows the site of bleeding and size of the tumor. The tumor bleeding stopped after treatment. ② After intervention chemotherapy and embolization the size of the primary tumor reduced quickly, but pathologic examination of the resected specimens revealed in complete coagulative necrosis of the tumor tissue in some cases. Conclusion\ ① Interventional chemotherapy and embolization are satisfactory in the treatment of bleeding from cancer of cervix. ② However surgery and/or radiation are still required.

关 键 词：宫颈癌 介入疗法 药物疗法 出血 疗效 动脉栓塞 

分 类 号：R737.330.5[医药卫生—肿瘤]