蚌埠市儿童青少年代谢综合征危险因素病例对照研究  

Case-control Study on Risk Factors of Metabolic Syndrome in Children and Adolescent of Bengbu

作　　者：席倩[1,2] 刘超[1] 刘刚[3] 付丽琳[2] 徐红[4] 孙虹云[2] 周维荣[2] 

机构地区：[1]南京医科大学附属第一医院内分泌科,江苏210029 [2]蚌埠市第三人民医院内分泌科 [3]蚌埠市第三人民医院检验科 [4]蚌埠市第三人民医院内分泌科

出　　处：《中国学校卫生》2010年第12期1483-1485,共3页Chinese Journal of School Health

基　　金：蚌埠市科技局资助项目(编号:蚌科[2007]30号)

摘　　要：目的分析蚌埠市儿童青少年代谢综合征(MS)流行情况及其危险因素,为成年期疾病的早期预防提供依据。方法根据蚌埠市2007年中小学生身高、体重体检结果进行体重正常、超重和肥胖学生的筛选,随机抽取921名7～18岁学生进行身高、体重、腰围、臀围、血压测量,同时采集空腹时静脉血测定血清总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和空腹血糖(FPG)、尿酸(UA)、超敏C反应蛋白(hs-CRP),并进行甲状腺B超检查。结果 3组学生MS检出率为肥胖组(28.4%)>超重组(11.9%)>正常体重组(1.7%),差异有统计学意义。除TC外,MS各危险因素及其他检测项目均数在MS组和非MS组之间差异均具有统计学意义(P值均<0.01)。MS各危险因素异常检出率在MS组与非MS组之间差异有统计学意义(P值均<0.01)。MS各组分检出率以中心性肥胖最常见,其次为高三酰甘油和高血压。结论随着儿童青少年体质量指数的增加,MS及各危险因素检出率显著增加。加强对儿童青少年MS指标监测已成为预防心血管疾病的必要措施。Objective To analyze the prevalence and risk factors of metabolic syndrome（MS）among children and adolescent in Bengbu,and to provide evidence for the early prevention of adult diseases.Methods Totally 921 children and adolescent from the whole primary schools and middle schools in Bengbu were divided into three groups：normal-weight,over weight and obese group,according to the results of height and weight in 2007 physical examination.Their height,weight,waist circumference（WC）,hip circumference,blood pressure,TC,TG,HDL-C,LDL-C,FPG,UA,hs-CRP were measured,and thyroid ultrasound was taken for each volunteer.Results There were significant differences of the prevalence of MS between different groups,obesity（28.4%）overweight（11.9%）normal（1.7%）.Except for TC,there were significant differences in each risk factor between MS and non-MS group（P0.01）.There were significant differences in prevalence of MS between MS and non-MS group（P0.01）.Besides central obesity,the most common component of MS was high TG and high blood pressure for the prevalence of MS.Conclusion The prevalence of MS abnormal components is increasing with the body weight.Supervision of MS indices is the necessary measure to prevent cardiovascular diseases.

关 键 词：代谢综合征X 危险因素 病例对照研究 青少年 

分 类 号：R339.35[医药卫生—人体生理学] R181.2[医药卫生—基础医学]