钇与吡啶-2,6-二甲酸和2,6-二氨基吡啶质子转移化合物的合成、表征及抗菌活性  

Synthesis,Characterization and Antibacterial Activity of Coordination Complex of Yttrium with 2,6-Pyridinedicarboxylate and 2,6-Pyridinediammonium

作　　者：蔡梦军[1] 陈建定[1] 

机构地区：[1]华东理工大学材料科学与工程学院,国家超细粉末工程研究中心,上海200237

出　　处：《华东理工大学学报（自然科学版）》2010年第6期786-791,共6页Journal of East China University of Science and Technology

基　　金：上海市青年科技启明星计划B类资助项目(08QB1401500);上海市重点学科和重点实验室资助项目(B502,08DZ2230500)

摘　　要：以吡啶-2,6-二甲酸(pydcH2)与2,6-二氨基吡啶(pyda)为原料,采用超声方法合成了质子转移化合物(pydaH2)2+(pydc)2-,再与Y(NO3)3反应合成了稀土金属钇与吡啶-2,6-二甲酸和2,6-二氨基吡啶的稀土金属有机配合物(pydaH2)Y2(pydc)4.10H2O。通过元素分析、红外、核磁共振、热重和差热分析等对质子转移化合物及稀土金属有机配合物进行了分析与表征,并研究了其对大肠杆菌和金黄色葡萄球菌的抗菌活性。结果表明稀土金属有机配合物(pydaH2)Y2(pydc)4.10H2O对大肠杆菌和金黄色葡萄球菌具有较高的抗菌活性。The rare earth metal yttrium coordination complex（pydaH2）（Y2（pydc）4）·10H2O was prepared by the reaction of Y（NO3）3 with proton transfer compound （pydaH2）^2＋（pydc）^2-,which was synthesized from 2,6-pyridinedicarboxylic acid（pydcH2） and 2,6-pyridinediamine（pyda） under ultrasonic.The chemical composition,structure and thermal properties of proton transfer complex and metal-organic coordination complex were characterized by elemental analysis, IR,NMR spectra,TGA and DTA.Furthermore,antibacterial activities of ligands and their complexes against Bacillus coli and Staphylococcus aureus were also studied.The results indicated that rare earth metal yttrium coordination complex（pydaH2）Y2（pydc）4·10H2O have higher antibacterial activity against Bacillus coli and Staphylococcus aureus than that of its free ligands and proton transfer compound（pydaH2）^2＋（pydc）^2-.

关 键 词：钇 吡啶-2 6-二甲酸 2 6-二氨基吡啶 质子转移化合物 配位化合物 抗菌活性 

分 类 号：O614.32[理学—无机化学] O622.5[理学—化学]