超高效液相色谱快速测定卷烟主流烟气中酚类化合物的研究  

An experimental study on rapid analysis of phenolic compounds in mainstream cigarette smoke by ultra performance liquid chromatography

作　　者：张婕[1] 周淑平[1] 耿召良[1] 张长云[1] 向章敏[1] 李卫红[1] 许冬青[1] 赵瑞娟[1] 

机构地区：[1]贵州省烟草科学研究所测试中心,贵州贵阳550000

出　　处：《化学工程师》2010年第12期29-31,38,共4页Chemical Engineer

基　　金：贵州省烟草公司科技计划项目(200920)

摘　　要：以卷烟主流烟气中酚类化合物的快速分析为内容,参照现有标准分析方法YC/T255-2008,研究了色谱条件由高效液相色谱(HPLC)变为超高效液相色谱(UPLC)的转换方法,建立了卷烟主流烟气中酚类化合物的UPLC快速分析方法。讨论了UPLC在实际应用中所遇到的问题及优缺点,为UPLC的应用开发提供参考。A rapid method for the simultaneous separation and quantitation ofphenolic compounds in mainstream cigarette smoke has been developed by studing the conversion of chromato-graphic conditions from HPLC（YC/T 255-2008 standard method） to ultraperformance liquid chromatography system（UPLC）.An experimental design was carried out and discussed to achieve the best elution gradient for separation of all the studied compounds with the best possible peak resolution and in the shortest possible analysis time.

关 键 词：超高效液相色谱 色谱条件转化 酚类化合物 快速测定 

分 类 号：O658[理学—分析化学]