急性脑梗死患者治疗的前后血清hs-CRP、IL-6和TNF-2水平测定的临床意义  

Clinical Significance of Measurement of Serum hs-CRP 、IL-6and TNF2 Levels after treatment in Patients with Acute Cerehral Infarction

作　　者：杨浚[1] 冯琴[1] 

机构地区：[1]克拉玛依市中心医院核医学科,新疆克拉玛依834000

出　　处：《医学信息》2011年第1期104-105,共2页Journal of Medical Information

摘　　要：目的择选了急性脑梗死患者治的前后血清hs—crp，IL6和TNF2水平的变化及临床意义。方法应用放射免疫分析法和免疫比浊法对33例急性脑梗死患者进行了治疗前后血清hs—CRP、IL-6和TNF-2水平测定，并与35名正常健康人作比较。结果急性脑梗死患者在治疗前血清hs—CRP，IL-6和TNF-2水平非常显著地高于正常人组cp〈001，经治疗3个月后与正常人比较无显著性差异（P〉005）。结论血清hsCRP、IL-6和TNF-2在急性脑梗死的病理过程中发挥重要作用．其水平的变化对于疾病的预后、发展及了解病情、指导治疗是有重要的临床价值。Objective To explore the Clinical Significance of charges of serum hs-CRP.lL-6and TNF2 levels after treatment in patients with acute cerebral infarction. Methods serum IL-6,TNF2（With RIA） serum hs-CRP （with immuno turbitigy method）levels were determined in 33 patients with acute cerebral infarction both before and ＇after treatment as well as in 35 controls. Result Before treatment serum hs-CRP. IL-6,TNF-2 Levels were Signifieanetly higher in the patients than those in controls（P〈0.01）.afrer for 3 months of treatment.the levels Were Significantly different from those in controls （P〉0.05）.Conclusions Serum hs-CRP,IL-6 and TNF-2 may play inpartant in the pathogenesis of acute cerebral infarction and Detsction their senan expression can be help in the assessment of diseases progress and prognosis.

关 键 词：急性脑梗 超敏C-反应蛋白 白细胞介素-6 肿瘤坏死因子-2 

分 类 号：R743.33[医药卫生—神经病学与精神病学]