胃癌术后早期肠内营养支持的研究  被引量:10

Research of early postoperative enteral nutrition in Patients with gastric cancer

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作  者:刘同运[1] 毛伟征[1] 李杨[1] 李林浩[1] 宋延强[1] 周少飞[1] 李谦[1] 

机构地区:[1]青岛大学医学院附属青岛市立医院普外科,山东青岛266071

出  处:《中国现代普通外科进展》2010年第11期868-870,共3页Chinese Journal of Current Advances in General Surgery

摘  要:目的:观察早期肠内营养(EEN)对胃癌患者术后恢复的影响。方法:将100例胃癌根治术后患者随机分为EEN组和肠外营养(PN)组,每组50例。2组均于术后第1天和第2天给予1/3、2/3目标量,第3- 8天维持目标量,2组患者基本等氮、等热量。于手术前1 d和术后第9天检测患者血清白蛋白(ALB)、转铁蛋白(TF)、前白蛋白(PA)、ALT、AST、总胆红素(TB)、CD3、CD4、CD8和CD4/CD8,记录营养支持不良反应发生率、胃肠道功能恢复时间、感染性并发症发生率、营养支持费用和住院天数。结果:EEN组和PN组的营养指标(ALB、TF、PA)及肝功能指标(ALT、AST、TB)差异无统计学意义(P〉0.05),但EEN组的免疫指标(CD3、CD4、CD4/CD8)高于PN组(P〈0.05)。EEN组和PN组营养支持不良反应的发生率差异无统计学意义(P〉0.05)。EEN组胃肠道功能恢复时间早于PN组(P〈0.01)。EEN组感染性并发症的发生率低于PN组(P〈0.05),EEN组营养支持费用和住院时间均少于PN组(P〈0.01)。结论:胃癌患者术后EEN比PN更为安全、经济、有效。LIU Tong-yun,MAO Wei-zheng,LI Yang,LI Lin-hao,SONG Yan-qiang,ZHOU Shao-fei,LI Qian Department of General Surgery,Qingdao Municipal Hospital Affiliated of Medical College Qingdao University(Qingdao 266400,China) Objective: To investigate the laboratory,clinical and economic results of early postoperative enteral nutrition(EEN) in patients with gastric cancer.Methods: One hundred patients with gastric cancer were randomly divided into two groups: early postoperative enteral nutrition(EEN) and parenteral nutrition(PN),The 1/3 and 2/3 target volumes were administered on the first and second postoperative days,and the full volume was given from third to eighth day in EEN and PN groups.The nutritional and immune parameters were detected one day before surgery and ninth day after surgery,clinical and economic results were collected in two groups.Results: The levels of ALB,TF,PA,ALT,AST,TB were similar to those of PN group(P〉0.05).and the CD3,CD4,CD4/CD8 were better in EEN group than PN group(P〈0.05).The side effects of EEN group were similar to those of PN group(P〉0.05).The recovery of bowel function was quicker in EEN group than that in PN(P〈0.01),as well as the complication rate and cost of nutrition support(P〈0.05,P〈0.01).Conclusion: EEN is better in safe,effective and economic than PN.

关 键 词:胃肿瘤 早期肠内营养 肠外营养 

分 类 号:R735.2[医药卫生—肿瘤]

 

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