恶性滋养细胞肿瘤34例临床分析  

Clinical analysis to 34 cases with gestationaI trophoblastic disease

作　　者：刘婷婷[1] 王杜平[1] 

机构地区：[1]珠海市妇幼保健院妇一科,广东珠海519001

出　　处：《海南医学》2011年第2期57-58,共2页Hainan Medical Journal

摘　　要：目的总结恶性滋养细胞肿瘤的诊治经验。方法回顾性分析我院2002-2009年收治的34例恶性滋养细胞肿瘤患者的临床资料。结果 26例侵蚀性葡萄胎中Ⅰ期17例,Ⅱ期5例,Ⅲ期3例,Ⅳ期1例为肝转移转上级医院;3例化疗后好转;22例近期治愈,近期治愈率为84.62%(22/26)。绒癌8例,Ⅰ期4例,Ⅱ期2例,Ⅲ期2例;其中1例绒癌Ⅲ期放弃治疗;1例绒癌Ⅱ期化疗后好转;6例近期治愈,近期治愈率为75%(6/8)。结论化学药物治疗恶性滋养细胞肿瘤有较好的疗效,是主要的治疗方法,早期诊断、早期治疗可提高恶性滋养细胞肿瘤的治愈率,在一些特定条件中可应用手术和放射治疗。Objective To analyze the clinical characteristics of gestational trophoblastic disease（GTD）.Methods From 2002 to 2009,clinical data of 34 cases with GTD were analyzed retrospectively.Results Among the 26 cases of invasive mole,17 cases were at stageⅠ,5 cases at stage Ⅱ,3 cases at stage Ⅲ,and 1 case with hepatic metastasis at stage Ⅳ;after chemotherapy,the symptoms of 3 cases were alleviated,22 cases were cured with a short-term cure rate of 84.62%.Among the 8 cases of choriocarcinoma,4 cases were at stageⅠ,2 cases at stageⅡ,and 2 cases at stage Ⅲ;1 case at stage Ⅲ abandoned treatment;after chemotherapy,1 case at stage Ⅱ was improved and 6 cases were cured with a short-term cure rate of 75%.Conclusion Chemotherapy is the main treatment on GTD.Early diagnosis and treatment could improve the cure rate of GTD.Under specified conditions,surgery and radiotherapy could be applied for GTD.

关 键 词：恶性滋养细胞肿瘤 侵蚀性葡萄胎 绒癌 

分 类 号：R730.5[医药卫生—肿瘤]