中西医结合治疗口腔念珠菌病疗效观察  

The Treatment of Traditional Chinese and Western Medicine for Oral Candidosis

作　　者：沈漪[1] 罗冬青[1] 

机构地区：[1]首都医科大学附属北京中医医院口腔科,北京100010

出　　处：《辽宁中医杂志》2011年第1期114-116,共3页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的:观察中西医结合治疗口腔念珠菌病的疗效。方法:108例口腔念珠菌病患者随机分为两组,治疗组(58例)按中医辨证分两型施治,同时口服氟康唑;对照组(50例)仅口服氟康唑,疗程2周。观察两组临床症状变化,临床有效率,停药后2周复诊,比较复发率。结果:两组治疗治疗后口干,口黏,黏膜烧灼感,心烦,纳差均有改善,与治疗前比较,差异有统计学意义(P<0.05),治疗组在改善口干,口黏和心烦的疗效优于对照组。治疗组有效率,复发率分别为94.8%和7.3%,对照组为78.0%和25.7%,治疗组疗效优于对照组。结论:中西医结合治疗口腔黏膜病可改善临床症状,提高有效率,降低复发率。Objective：To observe the curative effect of integrative medicine for treatment of oral candidosis. Methods：Totally 108 cases were randomized into two groups,50 in the control group and 58 in the treated group,both were treated with fluconazole,but to the treated group,integrative medical treatment was given additionally according to syndrome differentiation. The course for both groups was tow weeks. Changes of clinical symptoms,the effective rate were observed,and the next study was implemented two weeks after ending medication to compare the relapse rate between groups. Results：Symptoms as oral sticky,thirsty, mucosa burning,perturbation and anorexia were improved after treatment in both groups （P 0. 05） . The improvements of oral sticky,thirsty and perturbation in the treated group were better than those in the control group （P 0. 05） . The effective rate and relapse rate in the treated group was 94. 8% and 7. 3% respectively,while in the control group,78. 0% and 25. 7% respectively. Conclusion：Lntegrative medical treatment could improve the clinical symptoms with high efficacy and low relapse rate.

关 键 词：口腔念珠菌病 氟康唑 中西医结合疗法 

分 类 号：R781.54[医药卫生—口腔医学]