中成药中马兜铃酸A的UPLC/MS研究  

Research of Aristolochic Acid A in Chinese Traditional Patent Medicine by UPLC/MS

作　　者：周围[1,2] 牛宏亮 王波 刘红卫 贾松涛[2] 解迎双[4] 

机构地区：[1]甘肃出入境检验检疫局,兰州市嘉峪关东路387号730020 [2]甘肃农业大学食品科学与工程学院,兰州市730070 [3]甘肃省轻工业研究院,兰州市730000 [4]西北师范大学地理与环境科学学院,兰州市730070

出　　处：《光谱实验室》2011年第1期183-187,共5页Chinese Journal of Spectroscopy Laboratory

摘　　要：建立了中成药中马兜铃酸A的超高压液相色谱/质谱检测方法。测定结果表明,马兜铃酸A在超高压液相色谱/质谱的选择离子记录(SIR)中有较强的分子离子峰,检出限为0.1mg/kg,可以满足对中成药中马兜铃酸A测定要求。The method of UPLC/MS for analysis of Aristolochic Acid A in Chinese traditional patent medicine was established.The Aristolochic Acid A in selected ion recording（SIR） of UPLC/MS had a strong molecular ion peak,and the detection limit was 0.1mg/kg.The sensitivity is high enough to determine Aristolochic Acid A in Chinese traditional patent medicine.

关 键 词：超高压液相色谱/质谱联用仪 中成药 马兜铃酸A 

分 类 号：O657.63[理学—分析化学]