环境内分泌干扰物质的健康影响与作用机制  

THE HEALTH EFFECTS AND RELATED MECHANISM OF ENVIRONMENTAL ENDOCRINE DISRUPTORS

作　　者：时国庆[1] 李栋[1] 卢晓珅 王海鸥[1] 刘丽琴[1] 魏巍[1] 宣劲松[1] 

机构地区：[1]北京科技大学化学与生物工程学院生物科学与工程系,北京100083

出　　处：《环境化学》2011年第1期211-223,共13页Environmental Chemistry

基　　金：国家自然科学基金(20977007);中央高校基本科研业务费专项资金(FRF-BF-09-008A)资助

摘　　要：本文综述了环境内分泌干扰物质与人或动物生殖发育、行为智力、免疫功能、肥胖、糖尿病、癌症等异常或疾病的相关性及相关作用机制,讨论了其"低剂量效应"和"复合效应",对本领域今后发展的方向进行了探讨.Environmental endocrine disruptors（EDs） are widely distributed in the environment,and can threat the human and wildlife health by interfering with the normal endocrine balance.This paper reviews the ＂low-dose effect＂,the ＂mixture effects＂ of EDs,and the adverse effects and related mechanisms of EDs on human or animal reproduction and development,behavior and intelligence,immune function,obesity,diabetes,cancer and other abnormalities or related diseases.The direction of future development in this field is also discussed.

关 键 词：环境内分泌干扰物 健康 低剂量效应 复合效应 作用机制 

分 类 号：X503.1[环境科学与工程—环境工程]