毛母质癌临床病理分析  

An clinicopathological analysis of Pilomatrical carcinoma

作　　者：翟学锋[1] 马爱玲[1] 

机构地区：[1]宁夏医科大学附属医院,宁夏银川750004

出　　处：《宁夏医学杂志》2011年第1期45-46,F0002,共3页Ningxia Medical Journal

摘　　要：目的探讨毛母质癌的临床病理诊断及鉴别诊断。方法对6例毛母质癌进行临床、病理形态观察及免疫组织化学染色(CK7、CD10、Bcl-2、P63、Ki-67)。结果肿瘤位于真皮及皮下,由形态和大小不一的基底样细胞聚集形成大而不规则、境界不清的团块状结构,基底样细胞团内有灶状含有角化物的影细胞,核分裂多见。免疫组化:肿瘤细胞CK7(-),CD10(+),Bcl-2(+),P63(+),Ki-67(+)。结论毛母质癌根据临床及组织学形态即可诊断,当诊断困难时,免疫组织化学染色CK7、CD10、Bcl-2、P63、Ki-67有助于鉴别诊断。Objective To explore the clinicopathological features,diagnosis and differential diagnosis of pilomatrical carcinoma.Methods 6 cases with pilomatrical carcinoma were observed and analyzed by means of clinicopathologic data analysis,hematoxylin-eosin and immunohistochemical staining（CK7,CD10,Bcl-2,P63 and Ki-67）.Results Histologically,the tumor was large,asymmetrical,poorly circumscribed dermal or dermal-subcutaneous mass composed of several shaped and variously sized aggregations of basaloid cells.Foci of cornified material containing shadow cells are observed within the basaloid cell aggregations,mitoses frequent were observed.Immunohistochemically,the tumor cells with were positive for CD10,Bcl-2,P63 and Ki-67.Conclusion The pathological diagnosis of pilomatrical carcinoma mainly depends on the clinic and pathological morphology.If diagnosis is difficulty,the differential diagnosis can helped by immunohistochemical staining.

关 键 词：毛母质癌 临床病理学 免疫组化 鉴别诊断 

分 类 号：R739.5[医药卫生—肿瘤]