85例进展性卒中病因和危险因素特点探析  

The etiology and risk factors of progressive stroke: analysis of 85 cases.

作　　者：招远祺[1] 连颖妍[2] 赵敏[3] 蔡业峰[1] 黄燕[1] 

机构地区：[1]广东省中医院神经一科,广州510120 [2]广华医院-香港中文大学中医药临床研究服务中心 [3]广州中医药大学第二临床医学院,广州510405

出　　处：《广东医学》2010年第24期3200-3202,共3页Guangdong Medical Journal

基　　金：家"十一五"科技支撑计划资助项目(编号:2006BAI21B04);广州中医药大学科研创新基金(编号:09CX073)

摘　　要：目的采用TOAST分型法研究进展性卒中的病因和危险因素。方法回顾性分析85例43～87岁进展性卒中患者的临床资料,经影像学及其他病因学检查确定诊断。依据急性卒中治疗Org10172试验(TOAST)分型标准,确定患者的脑梗死病因分型,经统计学分析构成比及其主要危险因素的暴露情况。结果 (1)根据TOAST分型构成,大动脉粥样硬化型卒中占54.12%;小动脉闭塞型卒中占41.18%;心源性脑栓塞占1.18%;其他原因型卒中占1.18%;原因不明的缺血性卒中占2.34%。(2)危险因素暴露率最高为吸烟(32.94%),其次是脑梗死病史(29.41%),以下依次为糖尿病史(27.06%)、饮酒(15.29%)、冠心病史(8.23%)。结论进展性卒中的病因分型中,大动脉粥样硬化型和小动脉闭塞型卒中所占比例较高,危险因素以吸烟、脑梗死病史及糖尿病史的暴露率为高。Objective To study the etiology and risk factors of progressive stroke. Methods Patients aged between 43 and 87 with progressive stroke（n=85） were enrolled in the study of the etiology according to the TOAST classification criteria.Risk factors were analyzed according to data from subjects. Results Stroke with large-artery atherosclerosis,small artery occlusion,cardiac embolism,other demonstrated etiology and unknown etiology accounted for 54.12%,41.18%,1.18% and 2.34%,respectively.The major risk factors of progressive stroke included cigarette smoking（32.90%）,history of ischemic stroke（29.80%）,diabetes mellitus（27.10%）,alcohol consumption（15.30%） and history of coronary heart disease（8.20%）. Conclusion Large-artery atherosclerosis and small artery occlusion are the most common causes of progressive stroke.Cigarette smoking,history of ischemic stroke and history of diabetes mellitus account for the major risk factors.

关 键 词：进展性卒中 病因 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]