眼红斑痤疮111例临床分析  

Clinical analysis of 111 cases of ocular rosacea

作　　者：王开文[1] 

机构地区：[1]石河子大学医学院第一附属医眼科,新疆石河子832008

出　　处：《临床眼科杂志》2010年第6期511-513,共3页Journal of Clinical Ophthalmology

摘　　要：目的分析111例眼红斑痤疮的临床表现、并发症的发生率及主要治疗结果。方法除用肉眼观察外,主要用裂隙灯显微镜检查眼部,并用其弥散光线扫描观察面部皮肤的细微改变,特别是血管的异常。对眼干涩的患者进行泪液分泌试验及泪膜破裂时间测定。结果 111例中男性50例(45.0%),女性61例(55.0%);就诊年龄最小16岁,最大86岁,平均49岁,30～69岁年龄段占84.6%,其中睑缘结膜炎102例(91.9%),结膜炎9例(8.1%)。结膜充血及球结膜血管扩张变形或增生89例(80.2%)。结膜下出血6例(5.4%),球结膜淋巴水肿3例(2.7%),结节性结膜炎2例(1.8%)。表层点状角膜炎8例(9.2%),下方角膜血管翳5例(4.5%),丝状角膜炎4例(3.6%),角膜炎或溃疡3例(2.7%),干眼17例(15.3%),虹膜睫状体炎3例(2.7%),表层巩膜炎2例(1.8%),巩膜炎1例(0.9%),霰粒肿、麦粒肿各2例。面部皮肤血管扩张增生106例(95.5%),睑缘邻近皮肤血管扩张增生14例(12.6%),丘疹9例(8.1%),脓疱5例(4.5%),鼻前庭与鼻小柱间血管增生形成肿块2例(1.8%),肥大性酒渣鼻1例(0.9%)。结论眼红斑痤疮是一种常见病,尤其是中老年人更多见。侵犯眼表及眼前节某些组织,面部及眼表的血管改变是基本依据,再结合其他所见即明确诊断,丝状角膜炎、角膜溃疡经口服四环素治愈。Objective To evaluate the clinical features,complications and treatment used in 111 patients with ocular rosacea.Methods In addition to gross inspecting rosacea lesions of the eye and face,Slitlamp and microscope were used to detect their fine vascular anomalies. Tests of tear production and tear breakup time were performed in patients with Ocular dry sensation.Results Fifty（45.0%）of the 111 patients were men and 61（55.0%）were women. The age range at presentation was between 16 and 86 years（mean,49 years）.Blepharoconjunctivitis was found in 102 cases（91.9%）,conjunctivitis in 9 case（8.1%）.Besides hyperemia,vascular dilation and tortuosity or proliferation of the bulbar conjunctiva was present in 89 cases（80.2%）,subconjunctival hemorrhage in 6 cases（5.4%）,lymphoedema of the bulbar conjunctiva in 3 cases（2.7%）,nodular conjunctivitis in 2 cases（1.8%）.Superficial punctate keratitis was present in 8 cases（7.2%）,inferior cornea pannus in 5 cases（4.5%）,filamentary keratitis in 4 cases（3.6%）,keratitis or ulcer in 3 cases（2.7%）.Dry eye was noted in 17 cases（15.3%）,iridocyclitis in 3 cases（2.7%）,episcleritis in 2 cases（1.8%）.Chalazion and hardeolum were noted respectively in 2 cases. Facial vascnlar changes were found in 106 cases（95.5%）and vascular changes of the skin adjecent to lid margin in 14 cases with 9 cases having facial ones simultaneously,skin papules in 9 cases（8.1%）and pustules in 5 cases（4.5%）,a phyma from vascular proliferation about nostril in 2 cases（1.8%）and rhinophyma in 1 cases（0.9%）.Conclusion Ocular rosacea is a common disorder involving the skin and the eye. Especially in middle-aged and elder individuals.Vascular anomalies of the face and ocular surface are basic findings and additional critical sighns presented,blepharoconjunctivitis is a common one,make the diagnosis erident.

关 键 词：眼红斑痤疮 血管扩张增生 角膜病变 干眼 回顾性研究 

分 类 号：R771.3[医药卫生—眼科]