青年和老年乳癌的预后分析  

Prognosis difference between young and old breast cancer patients

作　　者：刘玉忠[1] 郭文斌[1] 张春福[1] 安伟德[2] 张庆广[3] 

机构地区：[1]大连市中心医院普外二科,116033 [2]大连医科大学第一附属医院普外三科,116011 [3]北京医科大学人民医院乳腺中心,北京市100044

出　　处：《中国普通外科杂志》1999年第5期335-337,共3页China Journal of General Surgery

摘　　要：目的　探讨青年和老年乳癌的预后。方法　对作者３ 所医院２０ 年间（１９７０ ～１９９０ 年） 随诊资料完整的３５ 岁以下青年乳癌１９７ 例和６５ 岁以上老年乳癌２６６ 例的临床特征及预后进行回顾性分析。结果　青年和老年乳癌发病率有所上升，其５ 年生存率分别为５５．３％（１０９／１９７）及６５．４％ （１７４／２６６） ，两者间无显著性差异（ Ｐ＞ ０．０５）。原发肿瘤＞ ５ ．０ ｃｍ ，临床Ⅲ期，腋淋巴结转移＞ ５ 枚或妊娠、哺乳期者，青年组预后较老年组差（ Ｐ ＜ ０ ．０１） 。结论　提高乳癌生存率的关键是早期发现，早期综合治疗，对青年乳癌的意义尤为重要。在临床Ⅱ，Ⅲ期青年组，通过综合治疗后可提高生存率。Objective To compare the difference in prognosis of breast cancer in young and old patients. Methods Abstract Objective To compare the difference in prognosis of breast cancer in young and old patients. Methods Retrospective analysis on clinical characteristics and prognosis based on the follow up data of 197 young patients aged below 35 years and 266 old patients aged above 65 years who were from 3 hospitals during 20 years (1970～1990). Results Incidence rate of breast cancer in both young and old patients increased recenlty. The five year survival rate was 55.3% (109/197) in young patients and 65.4% (174/266) in old patients respectively (P>0.05). Compared with the old patient, prognosis was significantly poor (P<0.01) for the young patient in cases of the diameter of lesion>5.0?cm, clinical stage Ⅲ, lymph nodes metastasis>5, pregnancy or lacation. Conclusions The key steps in improving the survival rate of patients with breast cancer are the early diagnosis and early comprehensive treatment, especially for the young patients in clinical stage Ⅱ and Ⅲ.

关 键 词：乳腺肿瘤 死亡率 存活率 预后 年龄 

分 类 号：R737.907[医药卫生—肿瘤]