卵黄样黄斑营养不良的光学相干断层扫描影像学特征  

Imaging characteristics of optical coherence tomography in vitelliform macular dystrophy

作　　者：李娟娟[1] 张文佳[1] 盛智超[1] 胡竹林[1] 

机构地区：[1]云南省红十字会医院眼科,云南省昆明市650021

出　　处：《眼科新进展》2011年第1期39-41,共3页Recent Advances in Ophthalmology

基　　金：云南省科技计划项目(编号:2009ZC175M)~~

摘　　要：目的探讨卵黄样黄斑营养不良各病变阶段光学相干断层扫描(optical coherence tomography,OCT)的影像学特征。方法回顾性分析6例(8眼)卵黄样黄斑营养不良患者的OCT图像特征,并与眼底特征、眼底荧光血管造影进行对照分析。结果卵黄样病变期患者眼底检查可见黄斑区卵圆形隆起病灶,OCT可见视网膜色素上皮层和光感受器层之间有一中等密度反射区域,随病变进展,沉积物厚度增高。萎缩期患者黄斑区见萎缩灶,OCT表现为视网膜色素上皮层脉络膜复合体弥漫性增厚,神经感觉层变薄,合并脉络膜新生血管形成时可见高反射的新生血管膜。结论详细的病史资料、眼底检查、眼底荧光血管造影以及OCT的联合应用,有助于更科学的分析卵黄样黄斑营养不良的临床特征和病理改变。Objective To evaluate the imaging characteristics of optical coherence tomography（OCT）in vitelliform macular dystrophy at different stages.Methods The imaging characteristics of OCT in 6 patients（8 eyes）with vitelliform macular dystrophy were retrospectively analyzed,which were compared with the results of their fundus examination and fundus fluorescein angiography.Results At the stage of vitelliform,the fundus examination disclosed a round elevated yellowish lesion,OCT showed an area of hyper reflectivity locating between the retinal pigment epithelium layer and the photoreceptor layer.With the progression of disease,the thickness of nerosensory was increased.At the stage of atrophy,the atrophic focus was observed in the macular area,OCT showed the retinal pigment epithelium-choroid complement was thick,the nerve layer was thin,and the high reflective vessel membrane was seen in the combined choroidal neovascularization.Conclusion OCT combined with detailed medical record,fundus examination and fluorescence fundus angiography can be helpful for the analysis of clinical characteristics and pathologic changes.

关 键 词：卵黄样黄斑营养不良 光学相干断层扫描 眼底荧光血管造影 

分 类 号：R774.5[医药卫生—眼科]