五倍子煎剂联合氨来呫诺糊剂局部治疗重型RAU的临床观察  

Traditional decoction Wubeizi joint Amlexanax paste local treating the major aphthous ulcer clinical observation.

作　　者：王阅春[1] 黄闽[1] 陈建刚[1] 

机构地区：[1]武汉大学中南医院口腔科,湖北武汉430071

出　　处：《临床口腔医学杂志》2011年第1期32-34,共3页Journal of Clinical Stomatology

摘　　要：目的:观察五倍子煎剂联合氨来呫诺糊剂局部治疗重型复发性口腔溃疡(RAU)的临床疗效。方法:给予氨来呫诺糊剂。4次/d×3 d溃疡面涂布治疗。以用药前后的平均溃疡期、疼痛指数和最大溃疡直径的差值作为疗效指标进行评价。结果:治疗组最大溃疡直径差值明显高于对照组(P<0.05);治疗组临床有效率为100%,优于对照组的66%(P<0.05)。结论:五倍子煎剂联合氨来呫诺糊剂能有效减轻重型RAU的疼痛症状,明显缩短溃疡愈合期。Objective：Observing clinical effect of traditional decoction Wubeizi joint Amlexanax paste local treatment of the major aphthous ulcer.Method：Selected 30 patients with o major aphthous ulcer were randomly divided into experimental and control groups.Decoction 50 g was given wet dressing joint 5 g：250 mg of Amlexanox paste or Amlexanox paste only 4 times/d,ulcer surface coating 3 d continuously.Before and after treatment in patients with oral ulcers,the average ulcer stage,ulcer pain index and the largest difference between the diameter of evaluation as a therapeutic index of drug efficacy.Result：Experimental group,significantly higher than the control groups in maximum ulcer diameter difference（P 0.05）.The clinical trial in the experimental group was 100 % effective,better than the control group 66 %（P 0.05）.Conclusion：Gall decoction Wubeizi combined Amlexanox paste can effectively reduce severe recurrent oral ulcer pain,ulcer healing was significantly shorter period.

关 键 词：五倍子 氨来呫诺糊剂 重型复发性口腔溃疡 局部治疗 

分 类 号：R781.5[医药卫生—口腔医学]