利用CT图像勾画前列腺癌尖部的研究  

Localization of the prostatic apex using CT for radiation treatment planning

作　　者：李晓梅[1] 高献书[1] 郭雪梅[2] 李雅刚[1] 王霄英[2] 

机构地区：[1]北京大学第一医院放疗科,100034 [2]北京大学第一医院医影像科,100034

出　　处：《中华放射肿瘤学杂志》2011年第1期45-48,共4页Chinese Journal of Radiation Oncology

摘　　要：目的 分析前列腺癌患者的CT与MRI图像,测量前列腺尖部与周围CT易辨认的解剖结构间关系,为应用CT图像勾画前列腺癌靶区提供参考依据.方法 回顾分析108例前列腺癌患者的CT与MRI图像,测最前列腺尖部到闭孔下缘、坐骨结节下缘、耻骨联合下缘及尿道球之间距离.测量前列腺体积,分析前列腺大小与尖部位置关系.结果 前列腺尖部位于尿道球上方（13.1±3.3）mm、闭孔下缘上方（11.0±5.4）mm;距离坐骨结节下缘（31.3±5.5）mm;中线矢状位上前列腺尖部在耻骨下缘上方（7.1±4.7）mm.前列腺体积大小与前列腺尖部到闭孔下缘的距离及前列腺尖部到尿道球间距离无相关性（R=0.07、-0.33,P均＞0.05）.结论 CT图像上勾画前列腺靶区至尿道球上6 mm可包括95%患者的前列腺尖部,勾画前列腺靶区至闭孔下缘可包括100%患者的前列腺尖部.Objective In this retrospective study, we analyzed the magnetic resonance imaging （MRI）and computed tomography（CT）scans of patients with prostate cancer to investigate the relationship between the apex of prostate and the anatomic structures visible in CT, and to provide evidence for localizing the prostatic apex in radiation treatment planning. Methods MRI and CT scans from 108 patients with prostate cancer were analyzed to measure the distance between the prostatic apex and the bottom of ischial tuberosities,the bottom of obturator foramen, the bottom of pubic symphysis and the bulb of the penis. The volume of prostate was calculated and the relationship between the size of the prostate and the localization of the prostatic apex was analyzed. Results The prostatic apex is located 13. 1 mm ±3. 3 mm superior to the bulb of the penis, 11.0 mm ± 5.4 mm superior to the bottom of obturator foramen, 31.3 mm ± 5.5 mm superior to the bottom of ischial tuberosities, and 7. 1 mm ± 4. 7 mm superior to the bottom of obturator foramen. There was no correlation between the size of prostate and the localization of the prostatic apex（R =0. 07、-0. 33, all P 〉 0. 05）. Conclusions Ninety-five percent of patients had a prostatic apex that is above the bulb of the penis 6 mm, and 100% of patients had a prostatic apex that is above the bottom of obturator foramen.

关 键 词：前列腺尖部 体层摄影术 X线计算机 磁共振成像 靶区勾画 

分 类 号：R737.25[医药卫生—肿瘤]