5-氟尿嘧啶治疗早期复发性翼状胬肉的临床研究  

Clinical study of 5-fluorouracil on the treatment of early recurrent pterygium

作　　者：张小文[1] 李勇[1] 袁慧敏[1] 

机构地区：[1]中国湖北省孝感市中心医院眼科,432000

出　　处：《国际眼科杂志》2011年第2期361-362,共2页International Eye Science

摘　　要：目的:观察5-氟尿嘧啶(5-FU)治疗早期复发性翼状胬肉的临床疗效。方法:早期复发性翼状胬肉患者48例采用结膜下注射5-FU,观察结膜角膜眼压及前房反应,定期随访观察。结果:随访6～24mo,48例复发病例中,痊愈加显效30例,有效12例,6例无效。2例结膜囊缩窄,6例继续进展再次手术。12例角膜上皮点状脱落,停药48h愈合。结论:5-FU结膜下注射是治疗早期复发性翼状胬肉的一种安全、简便、有效的方法。AIM：To investigate the clinical effect of 5-fluorouracil（5-FU） on the treatment of early recurrent pterygium.METHODS：Forty-eight case with recurrent pterygium were treated with 5-FU by subconjunctival injection.The intraocular pressure and anterior chamber reaction were observed in the regular follow-up.RESULTS：The treated patients with early recurrent pterygium were followed up for 6-24 months.Patients that were cured or with evident effect was 30 cases,effect 12 cases,invalid 6 cases.2 cases were with constriction of conjunctival sac,6 cases were performed operation again because of the disease progress.The shedding of corneal epithelial was healing 48 hours after withdrawl of drug.CONCLUSION：The subconjunctival injection of 5-FU is a useful method for the treatment of early recurrent pterygium.

关 键 词：复发性翼状胬肉 5-氟尿嘧啶 

分 类 号：R777.33[医药卫生—眼科]