他汀类药物防治帕金森病的临床效果及作用机制研究进展  

Efficacy and mechanism of statins in prevention and treatment of Parkinson disease: recent progress

作　　者：祁敏[1] 魏显招[2] 姜秀峰[3] 

机构地区：[1]第二军医大学长征临床医学院,上海200003 [2]第二军医大学长海临床医学院,上海200433 [3]第二军医大学长海医院神经外科,上海200433

出　　处：《第二军医大学学报》2011年第1期92-95,共4页Academic Journal of Second Military Medical University

摘　　要：他汀类药物是一类降血脂药,它们是羟甲基戊二酸单酰辅酶A还原酶的抑制剂。他汀类药物具有多效性,最近的研究表明其可能具有防治帕金森病的潜力。本文就近年来他汀类药物在防治帕金森病的临床效果及作用机制方面的研究进展作一综述。Statins are a class of hypolipidemic drugs,and they are HMG-CoA reductase inhibitors.Statins are pleiotropic;recent studies have suggested that they might have a potential for prevention and treatment of Parkinson disease.This paper reviews recent researches about the roles of statins in the prevention and therapy of Parkinson disease in the nearest few years.

关 键 词：他汀类药物 帕金森病 预防 治疗 

分 类 号：R742.5[医药卫生—神经病学与精神病学]