787例乳腺癌患者腋淋巴结转移的影响因素  被引量:4

Analysis of predictors of axillary node metastases in 787 breast cancer patients

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作  者:张渤[1] 张晓俊[1] 郭繁[1] 郑瑞林[1] 张国琛[1] 韩国晖[1] 梁小波[1] 高晋南[1] 

机构地区:[1]山西省肿瘤医院乳腺三科,太原030013

出  处:《中华肿瘤杂志》2011年第1期67-69,共3页Chinese Journal of Oncology

摘  要:目的 探讨乳腺癌腋淋巴结转移的影响因素.方法 回顾性分析2006年12月至2008年11月在山西省肿瘤医院诊治的乳腺癌患者.采用Logistic回归分析,检查乳腺癌腋淋巴结转移与患者年龄、肿瘤大小、肿瘤病理类型、雌激素受体(ER)、孕激素受体(PR)、人类表皮生长因子受体2(Her-2)等因素的关系.结果 1133例乳腺癌患者中,具有完整的腋淋巴结手术及其他临床病理资料者787例(69.5%).平均每例清扫淋巴结14.6枚,平均每例淋巴结转移3.5枚.肿瘤大小与淋巴结转移呈正相关.多变量Logistic回归分析显示,患者年龄、肿瘤大小、ER状态、肿瘤病理类型与乳腺癌腋淋巴结转移有显著的相关性(P〈0.05).结论 肿瘤大小、患者年龄、ER状态及病理类型是乳腺癌腋窝淋巴结转移的影响因素.Objective To explore the predictors of axillary nodal metastass in patients with breast cancer.Methods A retrospective study was performed using the clinicopathological data of breast cancer cases diagnosed and treated in our Hospital between Dec 2006 and Nov 2008.Logistic regression analysis was used to determine the predictors of axillary node positivity.Results The total number of patients was 1133.69.5% of them (787) had complete clinical and pathological data.The median age was 49 years old ( range 20-85 ).The average number of lymph nodes removed was 14.6 per person.The average number of involved nodes was 3.5 per person.Increasing tumor size was associated with increased risk of lymph node metastases.Assessed by multivariate analysis, the tumor size, age, ER status, and pathological type were significantly associated with node metastasis.Conclusions Axillary nodal metastases are significantly affected by the tumor size, ER status, age, and pathological type in breast cancer patients.

关 键 词:乳腺肿瘤 淋巴转移 LOGISTIC模型 

分 类 号:R737.9[医药卫生—肿瘤]

 

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