^(18)F-FDG PET/CT监测结肠癌术后复发转移  

Value of ^(18)F-FDG PET/CT in detection of recurrence and metastasis of postoperative colon cancer

作　　者：李崇佼[1] 兰晓莉[1] 张永学[1] 吴志坚[1] 贾清[1] 谭旭波[1] 王瑜[1] 田月丽[1] 魏昊[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院核医学科湖北省分子影像重点实验室,湖北武汉430022

出　　处：《中国医学影像技术》2011年第1期95-99,共5页Chinese Journal of Medical Imaging Technology

基　　金：国家高技术研究发展计划(863计划)项目资助(2008AA02Z426)

摘　　要：目的评价PET/CT监测结肠癌术后复发转移的价值。方法 收集结肠癌术后可疑复发转移患者78例,男46例,女32例。回顾性分析比较PET/CT、传统影像学与组织病理学诊断或临床随访资料之间的差异,并比较PET/CT与传统影像学诊断结肠癌术后可疑复发转移的价值。结果 78例中,54例经组织病理学诊断或临床随访确诊存在复发、转移。PET/CT诊断结肠癌术后总体复发转移的灵敏度及准确率明显优于传统影像学,灵敏度分别为90.74%和51.85%(P<0.01),准确率分别为89.74%和58.97%(P<0.01)。PET/CT诊断结肠癌术后局部复发转移的灵敏度及准确率亦明显优于传统影像学,灵敏度分别为90.91%和42.42%(P<0.01),准确率分别为96.15%和75.64%(P<0.01)。结论 PET/CT在诊断结肠癌术后可疑复发转移中具有较高的灵敏度及准确率,是一种较理想的监测方法。Objective To assess the diagnostic value of PET/CT in detection of recurrence and metastasis in patients with postoperative colon cancer.Methods A total of 78 patients were suspected with recurrence and metastasis of postoperative colon cancer,including 46 males and 32 females.The diagnostic results of PET/CT and traditional imaging were analyzed and compared with histopathological diagnosis or clinical follow-up data.Results In all 78 patients,recurrence and metastasis were confirmed in 54 patients with histopathological diagnosis or clinical follow-up data.The sensitivity and accuracy of PET/CT were higher than those of traditional imaging in diagnosis of all recurrence and metastasis of postoperative colon cancer,and the sensitivity and accuracy of PET/CT and traditional imaging was 90.74% and 51.85%（P0.01）,89.74% and 58.97%（P0.01）,respectively.The sensitivity and accuracy of PET/CT were also higher than those of traditional imaging in diagnosis of local recurrence and metastasis of postoperative colon cancer（90.91% vs.42.42%,P0.01;96.15% vs.75.64%,P0.01）,respectively.Conclusion PET/CT imaging has significantly higher sensitivity and accuracy than traditional imaging in detection of recurrence and metastasis of postoperative colon cancer.It is an ideal method to monitor the recurrence and metastasis of postoperative colon cancer.

关 键 词：结肠肿瘤 正电子发射型体层摄影术 肿瘤转移 复发 

分 类 号：R735.35[医药卫生—肿瘤] R817.4[医药卫生—临床医学]