螺旋CT评估射频消融治疗肾癌的疗效  

Evaluation on efficacy of radiofrequency ablation for renal cell carcinoma with multi-slice helical CT

作　　者：徐向军[1] 纪长威[1] 屈峰[1] 姚林方[1] 张士伟[1] 李笑弓[1] 张古田[1] 甘卫东[1] 郭宏骞[1] 

机构地区：[1]南京大学医学院附属鼓楼医院泌尿外科,江苏南京210008

出　　处：《中国医学影像技术》2011年第1期167-170,共4页Chinese Journal of Medical Imaging Technology

基　　金：江苏省"六大人才高峰"第五批项目

摘　　要：目的观察多层螺旋CT增强扫描评估射频消融术(RFA)治疗肾癌的疗效的价值。方法 分析37例患者共39个肾癌癌灶于行射频消融治疗术前、术后1个月及术后1年的增强CT图像上肿瘤最大截面积及其CT值的变化。结果 RFA后1个月肿瘤最大截面积较术前明显增大(P<0.05),RFA后1年肿瘤区域最大截面积较术前明显缩小(P<0.05)。RFA后1个月和1年肿瘤最大截面的CT值增强量(即增强扫描动脉相较平扫相上肿瘤区域CT值的增加量)较术前明显减小(P<0.05),而术后1年肿瘤CT值增强量与术后1个月相比差异无统计学意义(P=0.99)。RFA后1个月和1年肿瘤最大截面的CT值增强量95%CI分别为(3.26～6.22)HU、(2.62～6.82)HU,两者上限均<10HU。结论 多层螺旋CT增强扫描可作为射频消融治疗肾癌术后肿瘤区是否毁损完全的可靠的评价指标,完全毁损的标准为术后肿瘤区域CT值增强量<10HU。Objective To assess the value of multi-slice helical CT（MSCT） in renal cell carcinoma（RCC） treated with radiofrequency ablation（RFA）.Methods Thirty-seven patients with 39 renal tumors underwent RFA.All of them were examined with MSCT preoperatively and postoperatively.The largest cross-section of each tumor was figured out,and the CT value was recorded.Results The areas of the largest cross-section of tumors were significant different preoperatively and postoperatively（P0.05）,it increased 1 month after operation,but decreased 1 year later.The enhanced CT value of tumors of the largest cross-section was significantly lower than that of preoperative（P0.05）,but There was no significant difference between 1 year and 1 month after operation（P=0.99）.Ninety-five percent confidence intervals of the enhanced CT value of the largest cross-section of the tumors in 1 year and 1 month after operation was（3.26—6.22）HU and（2.62—6.82）HU,respectively,both upper bounds were less than 10 HU.Conclusion MSCT is valuable in evaluation on the efficacy of radiofrequency ablation for renal cell carcinoma.If the enhanced CT value is less than 10 HU,the tumor may be completely destroyed after RFA.

关 键 词：癌 肾细胞 导管消融 治疗效果 体层摄影术 X线计算机 

分 类 号：R737.11[医药卫生—肿瘤] R814.42[医药卫生—临床医学]