脑梗死后出血性转化的研究现状  

Current Research of Hemorrhagic Transformation after Cerebral Infarction

作　　者：宋道远[1] 殷梅[1] 

机构地区：[1]昆明医学院第二附属医院神经内科,昆明650101

出　　处：《医学综述》2011年第1期110-113,共4页Medical Recapitulate

摘　　要：脑卒中的发病率、复发率、致残率及致死率都很高,现已超过肿瘤占我国人口死因的首位。其中缺血性脑卒中的发病率最高,一部分患者脑梗死后容易继发出血性转化,为社会及家庭带来了很大的负担。随着缺血性脑卒中后静脉、动脉和动静脉联合溶栓研究的大量进行,出血性转化的危险因素和预测指标等引起了很大关注。相关研究表明,脑梗死后出血性转化与年龄、高血压、高血糖等密切相关,而尿蛋白、血浆细胞外基质金属蛋白酶等可以作为预测指标以便更加慎重地进行处理,减少损失。The stroke has a high morbidity, rate of recurrenceand disability, and mortality. Now it has become the first cause of death in Chinese population, surpassing cancer. Cerebral infarction is the most common type of stroke. Some patients have hemorrhagic transformation after cerebral infarction, resulting in a great burden on both patients＇ families and society. With the wide development of intravenous thrombolysis, intra-arterial thrombolysis, and even the research of the combined intravenous and intra-arterial thrembolysis, the risk factors and predictive factors of hemorrhagic transformation have drawn great attention. It is believed that hemorrhagic transformation after cerebral infarction is related to some contributing factors, such as age, hypertension,and high blood sugar. However, albuminuria and matrix metallopreteinases may predict the occurrence of hemorrhagic transformation after cerebral infarction.

关 键 词：脑梗死 出血性转化 预测指标 危险因素 

分 类 号：R743.33[医药卫生—神经病学与精神病学]