卵巢外腹膜浆液性乳头状癌临床病理分析  

CUnicopathologic analysis of extraovarian peritoneal serous papillary carcinoma

作　　者：李德昌[1] 任力[1] 李炜[2] 岳颖[1] 毛志远[1] 

机构地区：[1]空军总医院病理科,北京100142 [2]同济医学院中加肿瘤研究中心

出　　处：《中国医药》2011年第2期147-149,共3页China Medicine

摘　　要：目的分析卵巢外腹膜浆液性乳头状癌（EPSPC）临床病理特点及预后。方法结合文献资料回顾性分析空军总医院收治的3例EPSPC患者的临床资料、病理切片及随访资料，并重新行免疫组化染色。结果3例EPSPC患者血清CA125均升高。肿瘤以低柱状上皮细胞排列成大小、形态不规则乳头，细胞核大，可见砂粒体。过碘酸雪夫染色阳性，免疫组化染色：肿瘤细胞CA125、S-100、CD15、广谱细胞角蛋白阳性，孕激素受体、雌激素受体、Calretinin阴性。结论EPSPC发病率低、误诊率高，进行免疫组化等病理检测有利于EPSPC的早诊断、早治疗。Objective To analyze the clinicopathologic features and prognosis of extraovarian peritoneal serous papillary carcinoma（EPSPC）. Methods The clinical, pathological, immunohistochemistry and follow-up data of 3 cases of EPSPC were analyzed and literatures were reviewed. Results Serum cancer antigen（CA） -125 of 3 cases of EPSPC were increased. Low cotumnar epithelial tumor cells were arranged in irregular papillary shapes. Large nuclei and psammomma bodies were seen. Periodic acid schiff （PAS） is positive, immunohistochemical study showed CA-125, S-100, CD15, cytokeratin（pan） were positive and progesterone receptor, estrogen receptor, Calretinin were negative. Conclusions EPSPC is quite low incidence but the misdiagnosis rate is high, and the prognosis is rather poor. Diagnosis is based on hisitological characteristics supplemented with immunohistochemical findings.

关 键 词：腹膜肿瘤 癌 乳头状 病理学 临床 

分 类 号：R735.5[医药卫生—肿瘤]