3.0T磁共振磷谱对短跑运动员骨骼肌能量代谢的研究  

^(31)P-MRS evaluation of skeletal muscle energy, metabolism in sprinters

作　　者：秦斌[1] 徐化凤[1] 陈婷[1] 吴飞云[1] 齐静[1] 

机构地区：[1]南京医科大学第一附属医院放射科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2011年第1期37-39,57,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：国家自然科学基金资助(30700191);江苏省自然科学基金资助(BK2006578)

摘　　要：目的:采用3.0T磁共振磷谱(31P-MRS)技术分析经过系统训练的运动员骨骼肌能量代谢特点。方法:对14名短跑运动员和16名普通志愿者的股四头肌进行31P-MRS采集,利用Matlab软件进行无机磷(Pi)、磷酸肌酸(PCr)、β-ATP的定量分析,同时计算二磷酸腺苷(ADP)和细胞内pH值,比较两组受试者与能量代谢相关化合物的含量差异。结果:运动员组骨骼肌的PCr、ATP含量高于普通志愿者组,pH值略低于普通志愿者组。ADP等其他含磷化合物无显著性差异。结论:经过系统训练的运动员ATP及PCr明显高于非运动员,31P-MRS能够定量分析骨骼肌的能量代谢特点,对评价体育运动中科学训练具有独特的作用。Objective： To evaluate the energy metabolism of skeletal muscle in sprinters using 3.0 tesla phosphorus magnetic reso-nance spectroscopy（31P-MRS）.Methods： 31P-MRS was acquired from quadricep muscles in 14 trained sprinters and 16 non-trained healthy volunteers.Concentration of inorganic phosphate（Pi）,phosphocreatine（PCr）and adenosine triphosphate（ATP） was measured by matlab software.Concentration of adenosine diphosphate（ADP） and intracellular pH value was calculated from the biochemistry reaction equilibrium.Results： Concentration of PCr and ATP in the muscle of trained sprinters were significantly higher than those in the volunteers.Sprinters had lower pH value in skeletal muscle than volunteers did.No difference was observed in the concentration of ADP between two groups.Conclusion： Trained athlete have higher content of ATP and PCr indicating a more efficient mitochon-drial phosphorlation system,and 31P-MRS has important role in evaluating training effects in sports.

关 键 词：短跑运动员 磁共振磷谱 骨骼肌 能量代谢 

分 类 号：R817.1[医药卫生—影像医学与核医学]