基于MRI/CT融合的高级别胶质瘤术前、后放疗靶区勾画的对比研究  

A Comparative Study of Target Delineation Based on Pre-or Post-operative MRI/CT Fusion in Patients with High Grade Glioma

作　　者：黄敏[1] 肖芸[1] 李国庆[1] 邬蒙[1] 

机构地区：[1]江西省肿瘤医院,330029

出　　处：《实用癌症杂志》2011年第1期74-75,80,共3页The Practical Journal of Cancer

摘　　要：目的探讨术后放疗对高级别胶质瘤的临床疗效。方法对40例术后病理检查证实为高级别胶质瘤患者,术后2～4周内行放射治疗,均行MRI/CT定位,随机分为2组实施放疗。一组以术前MRI与术后CT(MRI术前/CT术后)融合为参照勾画靶区;另一组以术后MRI与术后CT(MRI术后/CT术后)融合为参照勾画靶区。随访复发时间和部位,评价两组疗效。结果 MRI术前/CT术后组平均复发时间及生存时间较MRI术后/CT术后组长,有统计学意义,MRI术后/CT术后组边缘复发及野外复发例数明显多于MRI术前/CT术后组。结论以MRI术前/CT术后融合为参照勾画靶区更精准,可明显提高高级别胶质瘤患者的生存率。Objective To evaluate the clinical efficacy of post-operative radiotherapy in patients with high grade glioma.Methods 40 patients with pathologically confirmed high grade glioma were randomized into 2 groups.The target volumes were delineated based on the fusion of preoperative MRI and postoperative CT in one group（MRI pre-/CT post-）,while the target was contoured based on post-operative MRI and CT in another group（MRI post/CT post）.The clinical efficacy was evaluated according to the relapse time and relapse location.Results The recurrence time and survival time of the MRI pre-/CT post-group were longer than those of the MRI post-/CT post-group.There were significantly more border or outside field recurrences in the MRI post-/CT post-group.Conclusion Target volume delineation based on the image fusion of preoperative MRI and postoperative CT is much more accurate and can markedly improve the survival rate.

关 键 词：MRI/CT融合 高级别胶质瘤 靶区勾画 

分 类 号：R739.4[医药卫生—肿瘤]